Abstract
Delirium has been for years the Cinderella of English-language psychiatry: taken for granted, ignored, and not considered worthy of study. Whatever the reasons for this neglect might be, several recent developments in psychiatry and psychology fully justify a reexamination of this syndrome and its conceptual framework. The growth of experimental psychopathology, and particularly the study of drug-induced model psychoses as well as of the psychological effects of variation of sensory input and of sleep deprivation, invite comparison with that “experiment of nature” which is delirium. The concept of consciousness has recovered its respectability in psychology and the class of disorders designated “disturbances of consciousness” has recently attracted the attention of scientists from various disciplines.111 Progress in the understanding of the neural substrate of conscious experience has been spearheaded by neuroanatomists and neurophysiologists.14,36 The rapid development of general hospital psychiatry has given access and opportunity for the study of psychiatric complications of somatic disease to an extent unparalleled in the history of psychiatry. Psychiatrists working on the medical and surgical wards must deal with the diagnostic and therapeutic problems of delirium and related states as part of their liaison work.86 There has been dissatisfaction with the current classification of the so-called organic brain syndromes and salutary recognition that their study “touches on the basic questions of the biological organization of drives, affects, and cognitive processes.”99 Current interest in cognition60 should extend to delirium in which disorganization of cognitive processes is the chief feature.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Abse WD:Hysteria and Related Mental Disorders. Bristol, Wright, 1966.
Adland ML. Review, case studies, therapy, and interpretation of the acute exhaustive psychoses.Psychiatr Quart21: 38–69, 1947.
Adolfson J: Deterioration of mental and motor functions in hyperbaric air.Scand J Psychol6: 26–32, 1965.
Allison, RS. Perseveration as a sign of diffuse and focal brain damage.Br Med J2: 1027–1032, 1966.
Arnold OH, Kryspin-Exner K: Das experimentelle Delir.Wien Z Nervenheilk22: 73–93, 1965.
Baker AB, Knutson J. Psychiatric aspects of uremia.Am J Psychiat102: 683–687, 1946.
Bash KW: Zur Psychopathologie akuter symptomatischer Psychosen.Nervenarzt28: 193–199, 1957.
Bellak, L, ed:Schizophrenia: A Review of the Syndrome. New York, Logos Press, 1958.
Bleuler M: Psychiatry of cerebral diseases.Br Med J2: 1233–1238, 1951.
Bleuler M, Willi J, Buehler HR:Akute psychische Begleiterscheinungen koerperlicher Krankelten. Stuttgart, Thieme, 1966.
Bonhoeffer, K: Die Psychosen im Gefolge von akuten Infektionen, Allgemeinerkrankungen und inneren Erkrankungen, in Aschaffenburg GL (ed).Handbuch der Psychiatrie, Spez. Teil 3, Leipzig, Deuticke, 1912, pp. 1–60.
Boor W de:Pharmakopsychologie und Psychopathologie. Springer, Berlin, 1956.
Brawley P, Pos, R: The informational underload (sensory deprivation) model in contemporary psychiatry.Can Psychiatr J12: 105–124, 1967.
Brodal A: Anatomical points of view on the alleged morphological basis of consciousness.Acta Neurochir (Wien)12: 166–186, 1964.
Brown S: On the intervention of symptoms in the infective exhaustive psychoses.J Nerv Ment Dis43: 518–531, 1916.
Burt C: The concept of consciousness.Br Psychol53: 229–242, 1962.
Cadilhac J, Ribstein M. The EEG in metabolic disorders.World Neurol2: 296–308, 1961.
Cameron ED: Studies in senile nocturnal delirium.Psychiatr quart15: 47–53, 1941.
Cameron N:Personality Development and Psychopathology. Boston, Houghton Mifflin, 1963.
Cameron N, Magaret A:Behavior Pathology. Boston, Houghton Mifflin, 1951.
Chapman LF, Thetford WN, Berlin L, Guthrie TC, Wolff HG: Highest integrative functions in man during stress, in Solomon HC, Cobb S, Penfield W (eds):The Brain and Human Behavior. [Proc Ass Res Nerv Ment Dis] 36:491–534, 1958.
Chapman LF, Wolff HG: Disease of the neopallium and impairment of the highest integrative functions.Med Clin North Am42: 677–689, 1958.
Cohen S: The toxic psychoses and allied states.Am J Med15: 813–828, 1953.
Cohen S, Klein HK: The delirious patient.Am J Nurs58: 685–687, 1958.
Collier RM: A holistic-organismic theory of consciousness.J Individ Psychol19: 17–26, 1963.
Conrad K: Die symptomatischen Psychosen, in Gruhle HW, Jung R, Mayer-Gross W, Mueller M (eds):Psychiatrie der Gegenwart, Band 2, pp. 369–436. Berlin, Springer, 1960.
Coppolino GA: Incidence of post-anesthetic delirium in a community hospital: A statistical study.Milit Med128: 238–241, 1963.
Crowell EB Jr, Ketchum JS: The treatment of scopolamine-induced delirium with physostigmine.Clin Pharmacol Ther8: 409–414, 1967.
Cutshall BJ: The Saunders-Sutton syndrome: An analysis of delirium tremens.Q J Stud Alcohol26: 423–448, 1965.
Davidson EA, Solomon P: The differentiation of delirium tremens from impending hepatic coma.J Ment Sci104: 326–333, 1958.
Dewan JG, Spaulding WB:The Organic Psychoses. Toronto, Toronto University Press, 1958.
Diagnostic and Statistical Manual of Mental Disorders. Washington, DC, American Psychiatry Association, 1952.
Ditman KS, Whittlesey JRB: Comparison of the LSD-25 experience and delirium tremens.Arch Gen Psychiatry (Chicago)1: 47–57, 1959.
Dulfano MJ, Ishikawa S: Hypercapnia: Mental changes and extrapulmonary complications.Ann Intern Med63: 829–841, 1965.
Ebaugh FG, Barnacle CH, Ewalt JR: Delirious episodes associated with artificial fever: A study of 200 cases.Am J Psychiatry23: 191–217, 1936.
Eccles JC (ed):Brain and Conscious Experience. New York, Springer, 1966.
Eckenhoff JE, Kneale DH, Dripps RD: The incidence and etiology of post-anesthetic excitement.Anesthesiology22: 667–673, 1961.
Engel GL, Romano J: Delirium, a syndrome of cerebral insufficiency.J Chron Dis9: 260–277, 1959.
Farber IJ: Acute brain syndrome.Dis Nerv Syst20: 296–299, 1959.
Fazekas JF, Alman RW:Coma: Biochemistry, Physiology and Therapeutic Principles. Springfield, II, Charles C Thomas, 1962.
Forgus RH:Perception. New York, McGraw-Hill, 1966.
Frantzen E: Wernicke’s encephalopathy.Acta Neurol Scand42: 426 - 441, 1966.
Freedman DK, Troll L, Mills AB, Baker P:Acute Organic Disorder Accompanied by Mental Symptoms. Sacramento, California Department of Mental Hygiene, 1965.
Gershon S, Olariu J: JB 329—A new psychotomimetic: Its antagonism by tetrahydroaminacrin and its comparison with LSD, mescaline and sernyl.J Neuropsychiatry1: 283–292, 1960.
Giesler R, Hurley PL, Person PH Jr:Survey of General Hospitals Admitting Psychiatric Patients. Washington, DC, US Dept. of Health, Education, and Welfare, 1966.
Grinker RR Sr, Miller J, Sabshin M, Nunn R, Nunnally JC:The Phenomena of Depressions. New York, Hoeber, 1961.
Gross MM, Goodenough D, Tobin M, Halpert E, Lepore D, Perlstein A, Sirota M, Dibianco J, Fuller R, Kishner I: Sleep disturbances and hallucinations in the acute alcoholic psychoses.J Nerv Ment Dis142: 493–514, 1966.
Gulevich G, Dement W, Johnson L: Psychiatric and EEG observations on a case of prolonged (264 hours) wakefulness.Arch Gen Psychiatry (Chicago)15: 29–35, 1966.
Guttman O: Psychic disturbances in typhus fever.Psychiatr Quart26: 478–491, 1952.
Hartley D:Observations on Man, His Duty, and His Expectations. London, Leake and Frederick, 1749.
Hazan SJ: Psychiatric complications following cardiac surgery: I. A review article.J Thorac Cardiovasc Surg51: 307–319, 1966.
Hebb DO:A Textbook of Psychology. Philadelphia, Saunders, 1958.
Hebb, DO: The American revolution.Am Psychol15: 735–745, 1960.
Henry DW, Mann AM: Diagnosis and treatment of delirium.Cana Med Assoc J93: 1156–1166, 1965.
Hernandez-Peon R: Physiological mechanisms in attention, in Russell RW (ed):Frontiers in Physiological Psychology. New York, Academic Press, 1966, pp 121–147.
Hilgard ER:Introduction to Psychology, ed 2. New York, Harcourt, Brace, 1957.
Hinkle LE Jr: The physiological state of the interrogation subject as it affects brain function, in Biderman AD, Zimmer H (eds):The Manipulation of Human Behavior. New York, Wiley, 1961, pp 19–50.
Hoch A: The problem of toxic-infectious psychoses.NY State Hosp Bull5: 384–392, 1912.
Hoch PH, Cattell JP, Pennes HH: Effects of drugs.Am J Psychiatry108: 585–589, 1952.
Holt RR: The emergence of cognitive psychology.J Am Psychoanal Assoc12: 650–665, 1964.
Horowitz MJ: The imagery of visual hallucinations.J Nerv Ment Dis138: 513–523, 1964.
Inglis J: Sensory deprivation and cognitive disorder.Br J Psychiatry111: 309–315, 1965.
Itil T: Quantitative EEG changes induced by anticholinergic drugs and their behavioral correlates in man.Recent Adv Biol Psychiatry8: 151–173, 1966.
Itil T, Fink M: Anticholinergic drug-induced delirium: Experimental modification, quantitative EEG and behavioral correlations.J Nerv Ment Dis143: 492–507, 1966.
Jackson JH: in Taylor J (ed):Selected Writings. New York, Basic Books. 1958, vols 1 and 2.
Jaspers K:General Psychopathology. Chicago, University of Chicago Press, 1963.
Kanner L:Child Psychiatry, ed 3. Springfield, III, Charles C Thomas, 1957.
Kasanin J: The syndrome of episodic confusions.Am J Psychiat93: 625–638, 1936.
Kiloh LG, Osselton JW:Clinical Electroencephalography. London, Butterworths, 1961.
Klein R, Mayer-Gross W:The Clinical Examination of Patients with Organic Cerebral Disease. London, Cassell, 1957.
Kleitman N: Sleep, Wakefulness, and consciousness.Psychol Bull54: 354–359, 1957.
Klüver H: Mechanisms of hallucinations, in McNemar Q, Merrill MA (eds):Studies in Personality. New York, McGraw-Hill, 1942, pp 175 - 207.
Kornfeld DS, Zimberg S, Malm JR: Psychiatric complications of open-heart surgery.N Engl J Med273: 287–292, 1965.
Kubie LS: The psychodynamic position on etiology, in Kruse HD (ed):Integrating the Approaches to Mental Disease, New York, Hoeber-Harper, 1957, p. 24.
Lehmann, J: Mental disturbances followed by stupor in a patient with carcinoidosis.Acta Psychiatr Scand42: 153–161, 1966.
Leiderman PH, Mendelson J, Wexler D, Solomon P: Sensory deprivation: Clinical aspects.Arch Intern Med (Chicago)101: 389–396, 1958.
Levin M: Delirium: A gap in psychiatric teaching.Am J Psychiatry107: 689–694, 1951.
Levin M: Toxic delirium precipitated by admission to the hospital.J Nerv Ment Dis116: 210–214, 1952.
Levin M: Perseveration at various levels of complexity, with comments on delirium.AMA Arch Neurol. Psychiatry73: 439–444, 1955.
Levin M: Thinking disturbances in delirium.AMA Arch Neurol Psychiatry75: 62–66, 1956.
Levin M: Varieties of disorientation.J Ment Sci102: 619–623, 1956.
Levy R: The immobilized patient and his psychologic well-being.Postgrad Med40: 73–77, 1966.
Linn L, Kahn RL, Coles R, Cohen J, Marshall D, Weinstein EA: Patterns of behavior disturbance following cataract extraction.Am J Psychiatry110: 281–289, 1953.
Lipowski ZJ: Psychopathology as a science: Its scope and tasks.Compr Psychiatry7: 175–182, 1966.
Lipowski ZJ: Review of consultation psychiatry and psychosomatic medicine: I. General principles.Psychosom Med29: 153–171, 1967.
Lipowski ZJ: Review of consultation psychiatry and psychosomatic medicine: II. Clinical aspects.Psychosom Med29: 201–224, 1967.
Litin EM: Mental reaction to trauma and hospitalization in the aged.JAMA162: 1522–1524, 1956.
Ludwig AM: Altered states of consciousness.Arch Gen Psychiatry (Chicago)15: 225–234, 1966.
Lunn V: On body hallucinations.Acta Psychiatr Scand41: 387–399, 1965.
Malkin M, Hirsch AC: Postanesthetic delirium and its treatment.Oral Surg21: 738–742, 1966.
Marjerrison G, Keogh RP: Electroencephalographic changes during brief periods of perceptual deprivation.Percept Mot Skills24: 611–615, 1967.
Mayer-Gross W, Slater E, Roth M:Clinical Psychiatry. London, Cassell, 1954.
McKegney PF: The intensive care syndrome.Conn Med30: 633–636, 1966.
Mendelson J, Solomon P, Lindemann E: Hallucinations of poliomyelitis patients during treatment in a respirator.J Nerv Ment Dis126: 421–428, 1958.
Meyer A: in Winters EE (ed):Collected Papers, Baltimore, Johns Hopkins Press, 1951, vol 3, pp 304–305.
Morris GO, Singer MT: Sleep deprivation: The context of consciousness.J Nerv Ment Dis143: 291–304, 1966.
Plum F, Posner JB:The Diagnosis of Stupor and Coma. Philadelphia, Davis, 1966.
Reding GR, Daniels RS: Organic brain syndromes in a general hospital.Am J Psychiatry120: 800–801, 1964.
Redlich FC, Freedman DX:The Theory and Practice of Psychiatry. New York, Basic Books, 1966.
Robins AL, Schappell A, Wortis B: Psychiatric manifestations of organic disease of the brain.Med Clin N Amer42: 711–721, 1958.
Robinson WG Jr: the toxic delirious reactions of old age, in Kaplan OJ (ed):Mental Disorders in Later Life. Stanford, Stanford University Press, 1956, pp 332–351.
Romano J. Engel GL: Physiologic and psychologic considerations of delirium.Med Clin North Am28: 629–638, 1944.
Romano J, Engel GL: Studies of delirium: I. Electroencephalographic data.AMA Arch Neurol Psychiatry51: 356–377, 1944.
Rosenfeld HA: Note on the psycho-pathology of confusional states in chronic schizophrenias.Int J Psychoanal31: 132–137, 1950.
Sarnoff CA, Haberer CE: The technique of studying disturbances of consciousness at altitude.J Aviat Med30: 231–240, 1959.
Schiller F: Consciousness reconsidered.AMA Arch Neurol Psychiatry67: 199–227, 1952.
Schuster MM, Iber FL: Psychosis with pancreatitis.Arch Intern Med (Chicago)116: 228–233, 1965.
Searles HF: Concerning a psychodynamic function of perplexity, confusion, suspicion and related mental states.Psychiatry15: 351–376, 1952.
Simon A, Cahan RB: The acute brain syndrome in geriatric patients.Psychiatr Res Rep16: 8–21, 1963.
Simson TP: Infection psychoses.Public Health Rep75: 451–462, 1960.
Small IF, Small JG, Fjeld SP, Hayden MP: Organic cognates of acute psychiatric illness.Am J Psychiatry122: 790–797, 1966.
Staub H, Thoelen H (eds):BewusstScinsstoerungen. Stuttgart, Thieme Verlag, 1961.
Stephens DA: Psychotoxic effects of benzhexol hydrochloride (Artane).Br J Psychiatry113: 213–218, 1967.
Stern ES: Acute confusional insanity and delirium.J Ment Sci90: 761–766, 1944.
Strachan RW, Henderson JG: Dementia and folate deficiency.Q J Med59: 189–204, 1967.
Summerskill WHJ, Davidson EA, Sherlock S, Steiner RE: The neuropsychiatric syndrome associated with hepatic cirrhosis and an extensive portal collateral circulation.Q J Med25: 245–266, 1956.
Titchener JL, Zwerling I, Gottschalk L, Levine M, Culbertson W, Cohen S, Silver H: Psychosis in surgical patients.Surg Gynecol Obstet102: 59–65, 1956.
Tucker WI: The prevention and management of toxic psychosis (post-operative psychosis).Lahey Clin Bull13: 268–271, 1964.
Tuke DH:A Dictionary of Psychological Medicine. Philadelphia, Blakiston, 1892.
Tyler RH: Neurological complications of dialysis, transplantation, and other forms of treatment in chronic uremia.Neurology (Minneap)15: 1081–1088, 1965.
Victor M, Adams RD. The acute confusional states, in Harrison TR, Adams RD, Bennett IL Jr, Resnik WH, Thorn GW, Wintrobe MM (eds):Principles of Internal Medicine, ed 4. New York, McGraw- Hill, 1962, pp 354–362.
Vojtechovsky M, Vitek V, Rysanek K: Experimentelle Psychose nach Verabreichung von Benactyzin.Arzneimittel-forsch16: 240–242, 1966.
Walker EF: The syndrome of delirium.Dis Nerv Syst9: 336–339, 1948.
Wallace AFC: Cultural determinants of response to hallucinatory experience.Arch Gen Psychiatry (Chicago)1: 58–69, 1959.
Weinmann HM: EEG changes in acute viral disease in infancy and childhood.Electroenceph Clin Neurophysiol22: 93, 1967.
Weinstein EA, Kahn RL:Denial of Illness. Springfield, III, Charles C Thomas, 1955.
Weisman AD, Hackett TP: Psychosis after eye surgery.N Engl J Med258: 1284–1289, 1958.
West LJ (ed):Hallucinations. New York, Grune & Stratton, 1962.
Whitty CWM, Zangwill OL (eds):Amnesia. London, Butterworths, 1966.
Willanger R, Klee A: Metamorphopsia and other visual disturbances with latency occurring in patients with diffuse cerebral lesions.Acta Neurol Scand42: 1–18, 1966.
Willis T:Two Discourses Concerning the Soul of Brutes. London, Bring, Harper and Leigh, 1683.
Wilson RE, Shagass C: Comparison of two drugs with psychotomimetic effects (LSD and Ditran).J Nerv Ment Dis138: 277–286, 1964.
Wohlrabe JC, Pitts FN Jr: Delirium and complex electrolyte disturbance.Dis Nerv Syst25: 44–47, 1965.
Wolff HG, Curran D: Nature of delirium and allied states.AMA Arch Neurol Psychiatry33: 1175–1215, 1935.
Ziskind E: Isolation stress in medical and mental illness.JAMA168: 1427–1431, 1958.
Ziskind E, Graham RW, Kuninobu L, Ainsworth R: The hypnoid syndrome in sensory deprivation.Recent Adv Biol Psychiatry5: 331–346, 1963.
Zubek, JP, MacNeill M: Studies on immobilization: Behavioral and EEG effects.Can J Psychol20: 316–334, 1966.
Zubek JP, Welch G: Electroencephalographic changes after prolonged sensory and perceptual deprivation.Science139: 1209–1210, 1963.
Zuckerman M: Perceptual isolation as a stress situation.Arch Gen Psychiatry (Chicago)11: 255–276, 1964.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1967 The Williams & Wilkins Co.
About this chapter
Cite this chapter
Lipowski, Z.J. (1967). Delirium, Clouding of Consciousness, and Confusion. In: Psychosomatic Medicine and Liaison Psychiatry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2509-3_14
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2509-3_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9517-4
Online ISBN: 978-1-4613-2509-3
eBook Packages: Springer Book Archive