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Immunopotentiators and Rheumatic Diseases

  • Chapter
Immunology of Rheumatic Diseases

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Abstract

A number of disparate therapeutic modalities have been utilized in the medical management of rheumatic diseases. Traditionally, treatments have developed empirically utilizing distinct classes of therapeutic modalities. Nonspecific antiinflammatory drugs and corticosteroids exert antipyretic, antiinflammatory, and analgesic effects and thus offer symptomatic relief, yet they have not been shown to prevent the development of damage to bone or cartilage or to alter the course of the disease. The second group includes diverse unrelated drugs such as gold compounds,d-penicillamine, and antimalarials. They have been shown to have the potential to affect the progress of the disease, inducing remissions in some patients and limiting disease-induced tissue damages at the expense of numerous side or toxic effects. Cytotoxic and immunosuppressive drugs are also utilized with variable efficacy and significant toxicity. Although all of these drugs have a variety of pharmacological activities, a common property for their partial effectiveness has not yet been clearly elucidated.

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Authors and Affiliations

  1. Faculté de Médecine, Laboratoire d’Immunologie, F-37032, Tours Cedex, France

    Gerard Renoux & Micheline Renoux

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  1. Gerard Renoux
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  2. Micheline Renoux
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  1. College of Medicine, University of California, Irvine, California, USA

    Sudhir Gupta M.D.,F.R.C.P.(C), F.A.C.P.

  2. Health Science Center, University of Texas, San Antonio, Texas, USA

    Norman Talal M.D.

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© 1985 Plenum Publishing Corporation

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Renoux, G., Renoux, M. (1985). Immunopotentiators and Rheumatic Diseases. In: Gupta, S., Talal, N. (eds) Immunology of Rheumatic Diseases. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2493-5_26

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  • DOI: https://doi.org/10.1007/978-1-4613-2493-5_26

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