Skip to main content

Hemocyanin: A Biological Copper Dioxygen Carrier

  • Chapter
Biochemistry of Dioxygen

Part of the book series: Biochemistry of the Elements ((BOTE,volume 4))

  • 107 Accesses

Abstract

Hemocyanin is a dioxygen-carrying copper protein found in crabs, snails, spiders, octopi, and certain other related animals (for a review, see Brunori et al., 1982). There are two copper atoms at the oxidation level of cuprous ion at each reaction center. The structure of hemocyanin has been derived from X-ray studies.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Brunori, M., Giardina, B., and Kuiper, H. A., 1982. Oxygen-transport proteins,Inorg. Biochem.3: 126 – 182.

    Article  CAS  Google Scholar 

  • Bulkowski, J. E., Burk, P. L., Ludmann, M.-F., and Osborn, J. A., 1977. Two metal substrate interactions: The reversible reaction of a CuI-CuI complex with CO and O2,J. Chem. Soc. Chem. Commun.1977: 498 – 499.

    Article  Google Scholar 

  • Co, M. S., and Hodgson, K. O., 1981. Copper site of deoxyhemocyanin: Structural evidence from X-ray absorption spectroscopy, J.Am. Chem. Soc.103: 3200 – 3201.

    Article  CAS  Google Scholar 

  • Co, M. S., Hodgson, X. 0., Eccles, T. K., and Lontie, R., 1981. Copper site of molluscan oxyhemocyanins: Structural evidence from X-ray absorption spectroscopy, J.Am. Chem. Soc.103: 984 – 986.

    CAS  Google Scholar 

  • Freedman, T. B., Loehr, J. S., and Loehr, T. M., 1976. A resonance Raman study of the copper protein hemocyanin: New evidence for the structure of the oxygen-binding site, J.Am. Chem. Soc. 98: 2809 – 2815.

    CAS  Google Scholar 

  • McKee, V., Dagdigian, J. V., Bau, R., and Reed, C. A., 1981. Copper(II) hemocyanin models, J.Am. Chem. Soc.103: 7000 – 7001.

    Article  CAS  Google Scholar 

  • Moss, T. H., Gould, D. C., Ehrenborg, A., Loehy, J. S., and Mason, H. S., 1973. Magnetic properties ofCancer magisterhemocyanin, J.Biol. Chem.12: 2444 – 2449.

    CAS  Google Scholar 

  • Simmons, M. G., and Wilson, L. J., 1978. A haemocyanin model: A synthetic copper(I) complex having imidazole ligands and reversible dioxygen activity, J.Chem. Soc. Chem. Commun.1978: 634.

    Article  Google Scholar 

  • Simmons, M. G., Merrill, C. L., Wilson, L. J., Bottomly, L. A., and Kadish, K. M., 1980. The (bis-2,6-[1-(2-imidazol-4-ylethylimino)ethyl]pyridine) copper(I) cation: A synthetic Cu oxygen carrier in solution as a potential model for oxy-hemocyanin, J.Chem. Soc. Dalton Trans.1980: 1827 – 1837.

    Article  Google Scholar 

  • Sorrell, T. N., and Jameson, D. L., 1982. An explanation for the observed stoichiometry of carbon monoxide binding to hemocyanin, J.Am. Chem. Soc.104: 2053 – 2054.

    Article  CAS  Google Scholar 

  • Thamann, T. J., Loehr, J. S., and Loehr, T. M., 1977. Resonance Raman study of oxyhemoglobin with unsymmetrically labeled oxygen, J.Am. Chem. Soc.99: 4187 – 4189.

    Article  PubMed  CAS  Google Scholar 

  • Torensma, R., and Phillips, R. C., 1983. Oxygen binding by Helix pomatra a-haemocyanin studied by X-ray absorption spectroscopy, Biochem J. 209:373–377

    PubMed  CAS  Google Scholar 

  • Van Holde, K. E., 1967. Physical studies of hemocyanins. III. Circular dichroism and absorption spectra,Biochemistry6: 93 – 99.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1985 1985 Plenum Press, New York

About this chapter

Cite this chapter

Ingraham, L.L., Meyer, D.L. (1985). Hemocyanin: A Biological Copper Dioxygen Carrier. In: Biochemistry of Dioxygen. Biochemistry of the Elements, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2475-1_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2475-1_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9501-3

  • Online ISBN: 978-1-4613-2475-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics