TMF, A Thymic Epithelial Glycoprotein: Chemotaxis of Hematopoietic Precursor Cells
T-cell precursors which migrate to the thymus have been described in fetal liver (Lepault and Weissman, 1981) and in adult bone-marrow (Weissman et al, 1977). The mechanism of entry of these cells into the thymus, as well as of subsequent intra-thymic differentiation events are largely unknown, although thymic stromal elements, particularly epithelial cells, have been singled out as playing a major role both through their secretions and by cell-to-cell contact.
KeywordsMigration Agar Paraffin HEPES Kelly
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