TMF, A Thymic Epithelial Glycoprotein: Chemotaxis of Hematopoietic Precursor Cells

  • E. F. Potworowski
  • K. W. Pyke
  • Teresa Brodniewicz-Proba
  • Maria Zelechowska

Abstract

T-cell precursors which migrate to the thymus have been described in fetal liver (Lepault and Weissman, 1981) and in adult bone-marrow (Weissman et al, 1977). The mechanism of entry of these cells into the thymus, as well as of subsequent intra-thymic differentiation events are largely unknown, although thymic stromal elements, particularly epithelial cells, have been singled out as playing a major role both through their secretions and by cell-to-cell contact.

Keywords

Migration Agar Paraffin HEPES Kelly 

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References

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • E. F. Potworowski
    • 1
  • K. W. Pyke
    • 2
  • Teresa Brodniewicz-Proba
    • 1
  • Maria Zelechowska
    • 1
  1. 1.Institut Armand-FrappierLavalCanada
  2. 2.Ludwig Institute for Cancer ResearchMelbourneAustralia

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