Abstract
Studies of MHC restriction in T cell antigen recognition (1) suggest that the two sets of multigene families, i.e. MHC class 1 and 2 genes on the one hand and T cell antigen receptor genes on the other, evolved in parallel. The notion of Jerne (2) that germ-line v-genes encode combining sites of antibodies or T cell receptors which have specificities for all MHC alleles of the species almost predicted the MHC restriction found several years later (1).
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© 1985 Plenum Press, New York
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Matsunaga, T. et al. (1985). Use of Transgenic Mice with Human MHC Class 1 Gene (HLA-A2). In: Klaus, G.G.B. (eds) Microenvironments in the Lymphoid System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2463-8_41
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DOI: https://doi.org/10.1007/978-1-4613-2463-8_41
Publisher Name: Springer, Boston, MA
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