Heterogeneity of Human Thymus Epithelial Cells Revealed by Monoclonal Anti-Epithelial Cell Antibodies
The epithelial cell matrix of the thymus, which is involved in the generation of T lymphocyte immunocompetence, shows considerable (cytological) heterogeneity. This phenomenon has been well-established in ultrastructural morphology (this issue, p 288),2 but also in expression of thymic hormone components in the cytoplasm.3 We started the analysis of the thymic microenvironment for antigenic heterogeneity by raising monoclonal antibodies to thymus stromal cells.
KeywordsBordetella Pertussis Freeze Tissue Section Human Thymus Thymus Stromal Cell Royal Postgraduate Medical School
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