Abstract
By constructing bone marrow chimaeras between F1 mice and either parent it becomes possible to determine whether any particular accessory cell type subject to renewal is derived from stem cells present in the donor bone marrow (b.m.). Necessary conditions are that the cell type can be identified and clearly distinguished from other cells, and that appropriate reagents are available to distinguish between cells of the F1 donor and parent recipient origin.
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References
C.D. Dijkstra, E.W.A. Kamperdijk, and E.A. Dopp. The ontogenetic development of the follicular dendritic cell, Cell Tissue Res. 236: 203 (1984)
J.H. Humphrey, and D. Grennan, Isolation and properties of follicular dendritic cells, Adv. Exp. Med. Biol. 149: 823 (1981)
J.H. Humphrey and D. Grennan, The origin of follicular dendritic cells in the mouse and the mechanism of trapping of immune complexes by them, Eur. J. Immunol. (In Press)
J.H. Humphrey and D. Grennan, Different macrophage populations distinguished by means of fluorescent polysaccharides. Recognition and properties of marginal zone macrophages. Eur. J. Immunol. 11: 221 (1981)
D. Gray, J. Lortan, I.C.M. MacLennan, G.D. Johnson, B. Platteau and H. Bazin, Evidence that static but not recirculating B cells are responsible for antibody against DNP on neutral polysaccharide. (This Volume)
P.L. Amlot, D. Grennan and J.H. Humphrey, Splenic dependence of the antibody response to TI-2 antigens (Submitted for publication)
E. van Vliet, M. Melis and W. van Ewijk, Marginal zone macrophages in the mouse spleen identified by a monoclonal antibody. 1. Anatomical correlation with a B cell sub- population, J. Histochem. Cytochem. (In Press)
E. Heinen, D. Radoux, D.Y. Mason, H. Stein, C. Kinet-Denoel, C. Lilet-Leclerq and J. Simar, Morphological and immuno- cytochemical characterisation of human follicular dendritic cells isolated from tonsils, (This Volume)
M.H. Kosco, A.K. Szakal, R. Gieringer and J.G. Tew, Cytological features of mouse follicular dendritic cells, (This Volume)
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© 1985 Plenum Press, New York
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Humphrey, J.H., Sundaram, V. (1985). Origin and Turnover of Follicular Dendritic Cells and Marginal Zone Macrophages in the Mouse Spleen. In: Klaus, G.G.B. (eds) Microenvironments in the Lymphoid System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2463-8_21
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DOI: https://doi.org/10.1007/978-1-4613-2463-8_21
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