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The Ontogenetic Development of the Follicular Dendritic Cell in Rat Spleen

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Microenvironments in the Lymphoid System

Abstract

Secondary follicles of lymphoid organs contain a highly specialized non-lymphoid cell type, the so-called follicular dendritic cells (FDC). FDC are cells with extraordinary long slender cell processes, which form an intricate labyrinth of invaginations11,12 in which antigen-antibody complexes can be trapped and retained for several weeks2. This trapping is believed to play a role in the induction of immunological memory17 or as feedback mechanisms regulating the immune response24.

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© 1985 Plenum Press, New York

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Dijkstra, C.D., Döpp, E.A., Kamperdijk, E.W.A. (1985). The Ontogenetic Development of the Follicular Dendritic Cell in Rat Spleen. In: Klaus, G.G.B. (eds) Microenvironments in the Lymphoid System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2463-8_20

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  • DOI: https://doi.org/10.1007/978-1-4613-2463-8_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9495-5

  • Online ISBN: 978-1-4613-2463-8

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