Abstract
Secondary follicles of lymphoid organs contain a highly specialized non-lymphoid cell type, the so-called follicular dendritic cells (FDC). FDC are cells with extraordinary long slender cell processes, which form an intricate labyrinth of invaginations11,12 in which antigen-antibody complexes can be trapped and retained for several weeks2. This trapping is believed to play a role in the induction of immunological memory17 or as feedback mechanisms regulating the immune response24.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
A.N. Barclay. Immunology 44:727 (1981).
L.L. Chen, J.C. Adam, and R.M. Steinman. J. Cell Biol. 77:148 (1978).
C.D. Dijkstra, N.J. van Tilburg, and E.A. Döpp. Cell Tissue Res. 223:545 (1982).
C.D. Dijkstra, and E.A. Döpp. Cell Tissue Res. 229:351 (1983).
C.D. Dijkstra, E.A. Döpp, P. Joling, and G. Kraal. Proc. 8th GCC, Cambridge (1984).
P. Eikelenboom. Cell Tissue Res. 195:445 (1978).
T.J. Flotte, T.A. Springer, and G.J. Thorbecke. Am. J. Pathol. 111:112 (1983).
R. van Furth, Z.A. Cohn, J.G. Hirsh, J.H. Humphrey, W.G. Spector, and H.L. Langevoort Bull WHO 46:845 (1972).
J. Gerdes, H. Stein, D.Y. Mason, and A. Ziegler. Virch. Arch. B 42:161 (1983).
P. Groscurth. Pathol. Rec. Pract. 169:235 (1980).
M.G. Hanna, and A.K. Szakal. J. Immunol. 101:949 (1968).
E. Heinen, C. Lilet-Leclerq, D.Y. Mason, H. Stein, J. Boniver, D. Radoux, C. Kinet-Denoël, and L.J. Simar. Eur. J. Immunol. 14:267 (1984).
U. Heuserman, K-H. Zurborn, L. Schroeder, and H.J. Stutte. Cell Tissue Res. 209:279 (1980).
D.A. Hume, A.P. Robinson, G.G. MacPherson, and S. Gordon. J. Exp. Med. 158:1522 (1983).
J.H. Humphrey, D. Grennan, and V. Sundaram. Eur. J. Immunol., in press (1984).
Y. Imai, K. Terashima, M. Matsuda, M. Dobashi, K. Maeda, and T. Kasajima. Rec. Adv. RES. Res. 21:51 (1983).
G.G.B. Klaus, J.H. Humphrey, A. Kunkl, and D.W. Dongworth. Immunol. Rev. 53:3 (1980).
F.G.M. Kroese, P. Eikelenboom, and N. van Rooijen. Dev. Comp. Immunol. Supp. 2:69 (1982).
C. Lilet-Leclerq, D. Radoux, E. Heinen, C. Kinet-Denoël, J-O. Degraigne, M-P. Houben-Defresne, and L.J. Simar. J. Immunol. Meth. 66:235 (1984).
F.J. Meyler. Acad. Thesis, Amsterdam, The Netherlands (1960).
M. Naiem, J. Gerdes, Z. Abdulaziz, H. Stein, and D.Y. Mason. J. Clin. Pathol. 36:167 (1983).
G.J.V. Nossal, A. Abbot, J. Mitchell, and Z. Lummus. J. Exp. Med. 127:277 (1968).
M.R. Parwaresh, H.J. Radzun, M-L. Hansmann, and K-P. Peters. Blood 62:585 (1983).
N. van Rooijen. In: Phylogeny of immunological memory, M.J. Manning, ed., Elsevier/North-Holland, Amsterdam, New York, Oxford (1980).
C.J. Secombes, M.J. Manning, and E.A. Ellis. Immunol. 47:101 (1982).
A.J.P. Veerman. Z. Immun. Forsch. Immunobiol. 150: 45 (1975).
A.J.P. Veerman, E.C. Hoefsmit, and H. Boere. Stain Technol. 49:111 (1974).
A. Villena, A. Zapata, J.M. Rivéra-Pomar, M.G. Barrutia, and J. Fongua. Cell Tissue Res. 229:219 (1983).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Plenum Press, New York
About this chapter
Cite this chapter
Dijkstra, C.D., Döpp, E.A., Kamperdijk, E.W.A. (1985). The Ontogenetic Development of the Follicular Dendritic Cell in Rat Spleen. In: Klaus, G.G.B. (eds) Microenvironments in the Lymphoid System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2463-8_20
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2463-8_20
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9495-5
Online ISBN: 978-1-4613-2463-8
eBook Packages: Springer Book Archive