Abstract
Arterial measurement procedures which have proven useful in controlled clinical trials or show promise for early use in controlled trials will be discussed. Excluded from this discussion are many arterial evaluation procedures used primarily in clinical practice to explore symptoms and select patients for surgery. Procedures now used in clinical trials all provide an image of the vessel or its lumen. The current gold standard for in vivo morphometry is selective arterial angiography which is invasive, but is discussed as a basis for comparisonm with other methods. Nuclear magnetic resonance imaging, although not developed to a point where it appears useful in clinical trials, is mentioned because it offers the exciting possibility of both structural imaging and arterial wall metabolic function imaging.
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© 1985 Plenum Press, New York
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Blankenhorn, D.H. (1985). Noninvasive Atherosclerosis Assessment for Controlled Clinical Trials. In: Kritchevsky, D., Holmes, W.L., Paoletti, R. (eds) Drugs Affecting Lipid Metabolism VIII. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2459-1_17
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DOI: https://doi.org/10.1007/978-1-4613-2459-1_17
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