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Use of Monoclonal Antibodies in Studies of Lipoprotein Structure and Function

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Book cover Drugs Affecting Lipid Metabolism VIII

Abstract

In order to probe the structure and function of apoB, monoclonal antibodies directed against human LDL were produced. The seven antibodies tested were found to be directed against five individual antigenic determinants of apoB in holo-LDL. One of the antibodies inhibited the binding of 125I-LDL to the apoB, E receptor of cultured human fibroblasts.

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© 1985 Plenum Press, New York

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Schonfeld, G., Tikkanen, M.J., Hahm, Ks. (1985). Use of Monoclonal Antibodies in Studies of Lipoprotein Structure and Function. In: Kritchevsky, D., Holmes, W.L., Paoletti, R. (eds) Drugs Affecting Lipid Metabolism VIII. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2459-1_12

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  • DOI: https://doi.org/10.1007/978-1-4613-2459-1_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9493-1

  • Online ISBN: 978-1-4613-2459-1

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