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On the Transposition and Evolution of Tn1721 and its Relatives

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Plasmids in Bacteria

Abstract

Transposition of Tn3-like elements involves cointegrate formation catalyzed by transposase and resolution of cointegrates catalyzed by resolvase (1).

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References

  1. Heffron, F. (1983) Tn3 and its relatives. InMobile Genetic Elements, J.A. Shapiro, ed. Academic Press, New York. p. 223.

    Google Scholar 

  2. Schmitt, R., J. Altenbuchner, and J. Grinsted (1981) Complementation of transposition functions encoded by transposons Tn501(HgR) and Tn1721(TcR). InMolecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids, S.B. Levy, R.C. Clowes, and E.L. Koenig, eds. Plenum, New York, pp. 359–370.

    Google Scholar 

  3. Grinsted, J., F. de la Cruz, J. Altenbuchner, and R. Schmitt (1982) Complementation of transposition oftnpA mutants of Tn3, Tn21 Tn501 and Tn1721.Plasmid 8:276–286.

    Article  PubMed  CAS  Google Scholar 

  4. Diver, W.P., J. Grinsted, D.C. Fritzinger, N.L. Brown, J. Altenbuchner, P. Rogowsky, and R. Schmitt (1983) DNA sequences of and complementation by thetnpR genes of Tn21, Tn501 and Tn1721.Mol. Gen. Genet. 181:189–193.

    Article  Google Scholar 

  5. Schmitt, R., E. Bernhard, and R. Mattes (1979) Characterisation of Tn1721, a new transposon containing tetracycline genes capable of amplification.Mol. Gen Genet. 172:53–65.

    Article  PubMed  CAS  Google Scholar 

  6. Schmitt, R., J. Altenbuchner, K. Wiebauer, W. Arnold, A. Pühler, and F. Schöffl (1981) Basis of transposition and gene amplification by Tn1721 and related tetracycline-resistance transposons.Cold Spring Harbor Symp. Quant. Biol. 45:59–65.

    PubMed  CAS  Google Scholar 

  7. Schöffl, F., W. Arnold, A. Pühler, J. Altenbuchner, and R. Schmitt (1981) The tetracycline resistance transposons Tn1721 and Tn1771 have three 38-base pair repeats and generate five-base pair direct repeats.Mol. Gen. Genet. 181:87–94.

    Article  PubMed  Google Scholar 

  8. Wiebauer, K., S. Schraml, S.W. Shales, and R. Schmitt (1981) Tetracylcine resistance transposon Tn1721:recA-dependent gene amplification and expression of tetracycline resistance.J. Bact. 147:851–859.

    PubMed  CAS  Google Scholar 

  9. Altenbuchner, J., and R. Schmitt (1983) Transposon Tn1721: Site-specific recombination generates deletions and inversions.Mol. Gen. Genet. 190:300–308.

    Article  PubMed  CAS  Google Scholar 

  10. Rogowsky, P., and R. Schmitt (1984) Resolution of a hybrid co-integrate between transposons Tn501 and Tn1721 defines the re-combination site.Mol. Gen. Genet. 193:162–166.

    Article  PubMed  CAS  Google Scholar 

  11. Heffron, F., B.J. McCarthy, H. Ohtsubo, and E. Ohtsubo (1979) DNA sequence analysis of the transposon Tn3: Three genes and three sites involved in transposition of Tn3.Cell 18:1153–1164.

    Article  PubMed  CAS  Google Scholar 

  12. Foster, T.J., M.A. Davis, D.E. Roberts, K. Takeshita, and N. Kleckner (1981) Genetic organization of transposon Tn10.Cell 23:201–213.

    Article  PubMed  CAS  Google Scholar 

  13. Mötsch, S., and R. Schmitt (1984) Replicon fusion mediated by a single-ended derivative of transposon Tn1721.Mol. Gen. Genet. (in press).

    Google Scholar 

  14. Avila, P., F. de la Cruz, E. Ward, and J. Grinsted (1984) Plasmids containing one inverted repeat of Tn21 can fuse with other plasmids in the presence of Tn21 transposase.Mol. Gen. Genet. (in press).

    Google Scholar 

  15. Harshey, R.M., and A.J. Bukhari (1981) A mechanism of DNA transposition.Proc. Natl. Acad. Sci., USA 78:1090–1094.

    Article  PubMed  CAS  Google Scholar 

  16. Galas, D.J., and M. Chandler (1981) On the molecular mechanism of transposition.Proc. Natl. Acad. Sci., USA 78:4858–4862.

    Article  PubMed  CAS  Google Scholar 

  17. de la Cruz, F., and J. Grinsted (1982) Genetic and molecular characterisation of Tn21, a multiple resistance transposon from R100.1.J. Bact. 151:222–228.

    PubMed  Google Scholar 

  18. Bennett, P.M., J. Grinsted, C.-L. Choi, and M.H. Richmond (1978) Characterization of Tn501, a transposon determining resistance to mercuric ions.Mol. Gen. Genet. 159:101–106.

    Article  PubMed  CAS  Google Scholar 

  19. Zieg, J., and M. Simon (1980) Analysis of the nucleotide sequence of an invertible controlling element.Proc. Natl. Acad. Sci., USA 77:4196–4200.

    Article  PubMed  CAS  Google Scholar 

  20. Altenbuchner, J., C.-L. Choi, J. Grinsted, R. Schmitt, and M.H. Richmond (1981) The transposons Tn501 (Hg) and Tn1721 (Tc) are related.Genet. Res., Camb. 37:285–289.

    Article  CAS  Google Scholar 

  21. Waters, S., P. Rogowsky, J. Grinsted, J. Altenbuchner, and R. Schmitt (1983) The tetracycline resistance determinants of RP1 and Tn1721: Nucleotide sequence analysis.Nucl. Acids Res. 11:6089–6105.

    Article  PubMed  CAS  Google Scholar 

  22. Kopecko, D.J., J. Bravet, and S.N. Cohen (1976) Involvement of multiple translocating DNA sequences and recombinational hot spots in the structural evolution of bacterial plasmids.J. Mol. Biol. 108:333–360.

    Article  PubMed  CAS  Google Scholar 

  23. Foster, T.J., H. Nakahara, A.A. Weiss, and S. Silver (1979) Transposon A-generated mutations in the mercuric resistance genes of plasmid R100.1.J. Bact. 140:176–181.

    Google Scholar 

  24. Grinsted, J., and N.L. Brown (1984) Tn501 contains a terminus of Tn21: Consequences for evolution and for complementation.Mol. Gen. Genet, (submitted for publication).

    Google Scholar 

  25. Tanaka, M., T. Yamamoto, and T. Sawai (1983) Evolution of complex resistance transposons from an ancestral mercury transposon.J. Bact. 153:1432–1438.

    PubMed  CAS  Google Scholar 

  26. Schmidt, F. (1984) The role of insertions, deletions, and sub-stitutions in the evolution of R6 related plasmids encoding aminoglycosides transferase ANT-(2‘’). Mol. Gen. Genet. (in press).

    Google Scholar 

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Author information

Authors and Affiliations

  1. Lehrstuhl für Genetik, Universität Regensburg, D-8400, Regensburg, Germany

    Rüdiger Schmitt, Sabine Mötsch & Peter Rogowsky

  2. Departamento de Bioquimica, Universidad de Santander, Santander, Spain

    Fernando de la Cruz

  3. Department of Microbiology, University of Bristol, BS8 1TD, Bristol, UK

    John Grinsted

Authors
  1. Rüdiger Schmitt
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  2. Sabine Mötsch
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  3. Peter Rogowsky
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  4. Fernando de la Cruz
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  5. John Grinsted
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Editor information

Editors and Affiliations

  1. University of California, San Diego, La Jolla, California, USA

    Donald R. Helinski

  2. Stanford University, Stanford, California, USA

    Stanley N. Cohen

  3. University of Michigan, Ann Harbor, Michigan, USA

    Don B. Clewell

  4. Genex Corporation, Gaithersburg, Maryland, USA

    David A. Jackson

  5. Council for Research Planning in Biological Sciences, Inc., Washington, D.C., USA

    Alexander Hollaender

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© 1985 Plenum Press, New York

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Schmitt, R., Mötsch, S., Rogowsky, P., de la Cruz, F., Grinsted, J. (1985). On the Transposition and Evolution of Tn1721 and its Relatives. In: Helinski, D.R., Cohen, S.N., Clewell, D.B., Jackson, D.A., Hollaender, A. (eds) Plasmids in Bacteria. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2447-8_8

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  • DOI: https://doi.org/10.1007/978-1-4613-2447-8_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9487-0

  • Online ISBN: 978-1-4613-2447-8

  • eBook Packages: Springer Book Archive

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