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Broad Host-Range Plasmid R1162: Replication, Incompatibility, and Copy-Number Control

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Plasmids in Bacteria

Abstract

R1162 is a small [8.7 kilobases (kb)]plasmid encoding resistance to sulfonamides (SuR) and streptomycin (SmR), and replicating with a high copy-number in Escherichia coli (at least 10 copies per chromosome) (1). The plasmid is not self-transmissible, but may be readily mobilized by certain other conjugative plasmids, such as those of the P-l incompatibility group (2). Originally isolated from Pseudomonas aeruginosa (3), R1162 has a broad host-range (1,4–6). Plasmids which appear very similar to R1162 have been isolated from diverse bacteria (1,7); many of these may be identical representatives of the same far-ranging plasmid. At present there do not seem to be any clear differences between R1162 and the best-studied member of this group, RSF1010 (from E. coli) (1).

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Author information

Authors and Affiliations

  1. Department of Microbiology, The University of Texas at Austin, 78712-1095, Experimental Science Building, 226, Austin, Texas, USA

    Richard J. Meyer, Lung-Shen Lin, Kyunghoon Kim & Michael A. Brasch

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  1. Richard J. Meyer
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  2. Lung-Shen Lin
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  3. Kyunghoon Kim
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  4. Michael A. Brasch
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Editor information

Editors and Affiliations

  1. University of California, San Diego, La Jolla, California, USA

    Donald R. Helinski

  2. Stanford University, Stanford, California, USA

    Stanley N. Cohen

  3. University of Michigan, Ann Harbor, Michigan, USA

    Don B. Clewell

  4. Genex Corporation, Gaithersburg, Maryland, USA

    David A. Jackson

  5. Council for Research Planning in Biological Sciences, Inc., Washington, D.C., USA

    Alexander Hollaender

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© 1985 Plenum Press, New York

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Meyer, R.J., Lin, LS., Kim, K., Brasch, M.A. (1985). Broad Host-Range Plasmid R1162: Replication, Incompatibility, and Copy-Number Control. In: Helinski, D.R., Cohen, S.N., Clewell, D.B., Jackson, D.A., Hollaender, A. (eds) Plasmids in Bacteria. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2447-8_16

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  • DOI: https://doi.org/10.1007/978-1-4613-2447-8_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9487-0

  • Online ISBN: 978-1-4613-2447-8

  • eBook Packages: Springer Book Archive

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