Abstract
Weanling rats and one-day-old chicks were fed diets containing 10% of either safflower or linseed oil. Blood was obtained at different times and plasma lipids were separated into triglycerides, nonesterified fatty acids, phospholipids and cholesteryl esters. Feeding linseed oil (53.1% 18:3 and 17.3% 18:2) instead of safflower oil (1.3% 18:3 and 70.0% 18:2) caused extensive replacement of arachidonic acid by 20:5ω3 in all lipid fractions in both species. The cholesteryl ester fraction was species-specific in that its polyunsaturated fatty acids were almost exclusively of the C18 type in chicks, whereas rats contained both C18and C20polyunsaturated fatty acids. Modification of the fatty acid profiles of plasma lipids by dietary means could be important in thrombocyte function and thrombogenesis, as well as in cholesterol transport and atherogenesis. It is suggested that in studies in humans, consideration of the relative intakes of ω3 and ω6-polyunsaturated fatty acids would be useful, in addition to the generally used P/S ratio.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Vergroesen, A.J. (1975) “The Role of Fats in Human Nutrition”, Academic Press, London.
FAO/WHO (1980) “Dietary Fats and Oils in Human Nutrition”, Food and Agriculture Organization of the United Nations, Rome.
Holman, R.T. (1968) in “Progress in the Chemistry of Fats and Other Lipids”, vol. 9, edited by R.T. Holman, Pergamon, Oxford, pp. 274–348.
Lemarchal, P. (1978) REV. franc. Corps Gras 25, 303–308.
Tinoco, J., Babcock, R., Hincenbergs, I., Meiwadowski, B., Miljanich, P. and Williams, M.A. (1979) Lipids 14, 166–173
Budowski, P., Hawkey, C.M. and Crawford, M.A. (1980) Ann. Nutr. Alim. 34, 389–400
Dyerberg, J., Bang, H.O., Moncada, S. and Vane, J. R. (1978) Lancet ii, 117–119.
AIN Report (1977) J.Nutr. 107, 1340–1348.
Bartov, I., Lipstein, B. Amtbornstein, S. (1974) Poultry Sci. 53, 115–124.
Sklan, D., Hurwitz, S., Budowski, P. and Ascarelli, 1. (1975) J. Nutr. 105, 57–63.
Skian, D.Volcani, R. and Budowski, P. (1971) J. Dairy Sci. 54, 515–519.
Dyerberg, J., Bang, H. O. and Hjorne, N. (1975) Am. J. Clin. Nutr. 28,958–966.
Dyerberg, J. and Bang, H.O. (1979) Haemostasis 8, 227–233.
Von Lossoncy, T.O., Ruiter, A., Bronsgeest-Shoute, H.C., van Gent, C.M. and Hermus, R.J.J. (1978) Am. J. Clin. Nutr. 31,1340–1346.
Van Gent, C.M., Luten, J. B., Bronsgeest, H.C. and Ruiter, A. (1979) Lancet U, 1749–1750.
Siess, W., Scherer, B., Bohling, B, Roth, P., Kurzmann, I. and Weber, P.C. (1980) Lancet i, 441–444.
Hwang, D.H. and Carroll, A.E. (1980) Am. J. Clin.Nutr. 33, 590–597.
White, D.A. (1973) in “Form and Function of Phospholipids”, 2nd ed., edited by G.B. Ansell, R.M.C. Dawson and J.N. Hawthorne, Elsevier, Amsterdam, pp. 441–482.
Mohrhauer, H. and Holman, R.T. (1963). J. Lipid Res. 4, 151–159.
Poovaiah, P. B., Tinoco, J. and Lyman, R.L. (1976) Lipids 11, 194–202.
Witting, L. A., Harvey, C.C., Century, B. and Horwitt, M. K. (1961) O. Lipid Res. 2, 412–418.
Schlenk, H., Sand, D. M. and Gellerman, J.L. (1969) Biochim.Biophys. Acta 187, 201–207.
Hornstra, G., Haddeman, E. and ten Hoor, F. (1979) Lancet ii, 1080.
Mohrhauer, H. and Holman, R.T. (1963) J.Nutr. 81, 67–74.
Brenner, R.R. and Peluffo, R.O. (1966) J. Biol. Chem. 241, 5213–5219.
Mead, J. F. and Fulco, A. J, (1976) “The Unsaturated and Polyunsaturated Fatty Acids in Health and Disease” Chas. C. Thomas, Springfield, Illinois.
Dyerberg, J., Bang, H.O. and Aagaard, O. (1980) Lancet i, 199.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Plenum Press, New York
About this chapter
Cite this chapter
Budowski, P., Machtomi, E., Bartov, I. (1985). Fatty Acid Composition of Four Lipid Classes in Plasma of Rats and Chicks Receiving Linoleic and α-Linolenic Acids in their Diets. In: Halpern, M.J. (eds) Lipid Metabolism and Its Pathology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2445-4_21
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2445-4_21
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9486-3
Online ISBN: 978-1-4613-2445-4
eBook Packages: Springer Book Archive