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Control System Concepts and Approaches in Clinical Medicine

  • E. R. Carson
  • D. G. Cramp
  • L. Finkelstein
  • D. Ingram

Abstract

Control system concepts and approaches, derived mainly from engineering, have been found to be of great value when applied in other areas of science and technology. Nowhere is this more apparent than in medicine. In this chapter some general ideas concerning the nature of such an approach will be outlined. It will be shown how the health care system can be viewed as a control problem, how the techniques of signal analysis and mathematical modelling can be applied in patient management, and how the doctor-patient relationship must be seen within the wider context of a total health care system.

Keywords

Control System Model Arterial Oxygen Partial Pressure Trend Prediction Experimental Test Data Adaptive Fitting 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Adams, J. M., Attinger, E. O., and Attinger, F. M., 1978, Cluster analysis of respiratory time series,Biol. Cybern., 28: 183.PubMedCrossRefGoogle Scholar
  2. Albisser, A. M., 1979, Devices for the control of diabetes mellitus,Proc. IEEE, 67: 1308.CrossRefGoogle Scholar
  3. Beneken, J. E. W., Blom, J. A., Jorritsma, S. F., Nandorff, A., and Spierdijk, J., 1979, Prognosis, trend, prediction and models in patient management,J. Biomed. Eng., 1: 185.PubMedCrossRefGoogle Scholar
  4. Berzuini, C., and Stefanelli, M., 1982, KIRON: A computer system and a methodology applicable to the study of erythroid disorders,Comput. Biomed. Res., 15: 361.PubMedCrossRefGoogle Scholar
  5. Bloch, R., Ingram, D., Sweeney, G. D., Ahmed, K., and Dickinson, C. J., 1980, MacDope: a simulation of drug disposition in the human body. Mathematical considerations,J. Theoret. Biol., 87: 211.CrossRefGoogle Scholar
  6. Brown, B. H., Ashbury, A. J., Linkens, D. A., Perks, P., and Anthony, M., 1980, Closed-loop control of muscle relaxation during surgery,Clin. Phys. Physiol. Meas., 1: 203.CrossRefGoogle Scholar
  7. Cantrill, S. V., 1979, Computerisation of the problem orientated record, in: “Problem Orientated Medical Records”, J. C. Petrie and N. Mclntyre, eds., Churchill Livingstone, Edinburgh: 176.Google Scholar
  8. Carson, E. R., Cobelli, C., and Finkelstein, L., 1981, Modeling and identification of metabolic systems,Am. J. Physiol., 240: R120.PubMedGoogle Scholar
  9. Carson, E. R., Cobelli, C., and Finkelstein, L., 1983, “Mathematical Modeling of Metabolic and Endocrine Systems: Model Formulation, Identification and Validation”, Wiley, New York.Google Scholar
  10. Chi1coat, R. T., 1980, A review of the control of the depth of anaesthesia,Trans. Inst. Meas. Contr., 2: 38.CrossRefGoogle Scholar
  11. Cobelli, C., Carson, E. R., Finkelstein, L., and Leaning, M. S., 1984, The validation of simple and complex models in physiology and medicine,Am. J. Physiol., 246: R259.PubMedGoogle Scholar
  12. Dickinson, C. J., 1977, “A Computer Model of Human Respiration”, MTP, Lancaster.Google Scholar
  13. Edwards, P. R., Britton, K. E., Carson, E. R., Ekins, R. P., and Finkelstein, L., 1977, A control system approach to thyroid health care, in: “Medinfo 77”, D. B. Shires and H. Wolf, eds., North Holland, Amsterdam: 507.Google Scholar
  14. Edwards, P. R., Britton, K. E., Carson, E. R., Ekins, R. P., and Finkelstein, L., 1978, A control system approach to the management of thyroid disease, in: “A Link Between Science and Application of Automatic Control”, A. Niemi, ed., Pergamon, Oxford: 541.Google Scholar
  15. Gheorghe, A. V., Bali, H. N., Hill, W. J., and Carson, E. R., 1976, Dynamic decision models for clinical diagnosis,Int. J. Biomed. Comput., 7: 81.PubMedCrossRefGoogle Scholar
  16. Godfrey, K. R., 1983, “Compartmental Models and their Application”, Academic Press, London.Google Scholar
  17. Jacobs, O. L. R., Bullingham, R. E. S., McQuay, H. J., and Reasbeck, M. P., 1983, On-line estimation in the control of post-operative pain, in: “Identification and System Parameter Estimation 1982”, G. A. Bekey and G. W. Saridis, eds., Pergamon, Oxford: 890.Google Scholar
  18. Kitabachi, A. E., Fisher, J. N., Matteri, R., and Murphy, M. B., 1983, The use of continuous insulin delivery systems in treatment of diabetes mellitus, Adv. Intern. Med., 28: 449.Google Scholar
  19. Leaning, M. S., Uttamsingh, R. J., Carson, E. R., and Finkelstein, L., 1982, A systems model of renal dialysis: formulation, validation and identification, Proc. IEE (Part A), 129: 707.Google Scholar
  20. Leaning, M. S., Pullen, H. E., Carson, E. R., and Finkelstein, L., 1983, Modelling a complex biological system: the human cardiovascular system - I Methodology and model description, Trans. Inst. Meas. Contr., 5: 71.CrossRefGoogle Scholar
  21. Mclntyre, N., and Wadbrook, D., 1981, Instant information, Health and Social Service J., August 14, 980.Google Scholar
  22. Molino, G. P., Milanese, M., Villa, A., Cavanna, A., and Gaiolano, G. P., 1978, Discrimination of hepatobiliary diseases by the evaluation of bromosulfophthalein blood kinetics, J. Lab. Clin. Med., 91: 396.PubMedGoogle Scholar
  23. Naghdy, F., 1981, “Monitoring and Forecasting the Status of Post- cardiac Surgical Patients”, Ph.D. Thesis, University of Bradford.Google Scholar
  24. Price, D. J., Dugdale, R. E., and Mason, J., 1980, The control of ICP using three asynchronous closed loops, in: “Intracranial Pressure IV”, K. Shulman, ed., Springer-Verlag, Berlin: 395.Google Scholar
  25. Slate, J. B., and Sheppard, L. C., 1981, Automatic control of blood pressure by drug infusion, Proc. IEE (Part A), 129: 639.Google Scholar
  26. Smallwood, R. D., Sondik, E. J., and Offensend, F. J., 1971, Toward an integrated methodology for the analysis of health care systems, Oper. Res., 18: 1300.CrossRefGoogle Scholar
  27. Weed, L. L., 1969, “Medical Records, Medical Education and Patient Care”, Case Western Reserve University Press, Cleveland.Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • E. R. Carson
  • D. G. Cramp
  • L. Finkelstein
  • D. Ingram

There are no affiliations available

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