Abstract
Development of the centrencephalic concept in the study of epilepsy was guided by extensive electrographic and clinical observations by the Montreal school, which excelled in excising the focal cortical area of epileptogenesis (Penfield and Jasper, 1954). This theory attempted to explain generalized seizures by postulating that an epileptogenic “focus” existed in a hypothetical network of neurons in the higher brainstem near the midline, having equal and close to-and-fro interconnections with widespread cerebral cortical areas of both hemispheres by virtue of its central location. Penfield and Jasper were careful to state that they did not envisage the “centrencephalon” in anatomical terms and they emphasized further the importance of cortico-subcortico-cortical interaction for electroclinical manifestations of generalized seizures. This theory was convenient and useful in explaining generalized 3/sec spike and wave discharges as well as for explaining the secondary bilateral synchrony frequently resulting from lateralized pathophysiology.
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References
Avoli, M., and Gloor, P., 1981, The effects of transient functional depression of the thalamus on spindle and on bilateral synchronous epileptic discharges of feline generalized penicillin epilepsy, Epilepsia 22:443–52.
Avoli, M., and Gloor, P., 1982, Thalamic involvement in feline generalized epilepsy:Data from unilaterally and bilaterally decorticated animals, Abstract, Eastern EEG Ski Meeting, March 5.
Bach-Y-Rita, G., Poncet, M., and Naquet, R., 1969, Morphological and spatiotemporal evolution of ictal discharges induced by cardiazol in the presence of various cortico-diencephalic lesions in cats, in:The Physiopathogenesis of the Epilepsies( H. Gastaut, H. H. Jasper, J. Bancaud, and A. Waltregny, eds.), C. C. Thomas, Springfield, Illinois, pp. 237–248.
Bancaud, J., Talairach, J., Morel, P., Bresson, M., Bonis, A., Geir, S., Hemon, H., and Buser, P., 1974, General epileptic seizures elicited by electrical stimulation of the frontal lobe in man, Electroencephalogr. Clin. Neurophysiol. 37:275–382.
Bogen, J. E., Sperry, R. W., and Vogel, P. J., 1969, Commissural section and the propagation of seizures, in:Basic Mechanisms of the Epilepsies( H. H. Jasper, A. A. Ward, and A. Pope, eds.), Little, Brown, Boston, pp. 439–140.
Catier, J., Choux, M., Cordeau, J. P., Dimov, S., Riche, D., Eberhard, A., and Naquet, R., 1970, Resultats préliminaries des éffets électrographiques de la section du corps calleux chez le Papio papio, Photo. Rev. Neurol. 122:521–522.
Churchill, J. A., 1959, The relationship of epilepsy to breech delivery, Electroencephalogr. Clin. Neurophysiol. 11:1–12.
Collins, R., 1978, Kindling of neuroanatomic pathways during recurrent focal penicillin seizures, Brain Res. 150:503–517.
Erickson, T. C., 1940, Spread of the epileptic discharge, Arch. Neurol. Psychiatry 32:429–452
French, J. D., Gernandt, B. E., and Linvingston, R. B., 1955, Regional differences in seizure susceptibility in monkey cortex, Arch. Neurol. Psychiatry 18:74–95.
Garretson, H., Gloor, P., and Rasmussen, T., 1966, Intracarotid amobarbital and metrazol test for the study of epileptiform discharges in man:A note on its technique, Electroencephalogr. Clin. Neurophysiol. 21:607–610.
Gloor, P., 1968, Generalized cortico-reticular epilepsies. Some considerations on the pathophysiology of generalized bilaterally synchronous spike and wave discharge, Epilepsia 9:249–263.
Gloor, P., 1969, Neurophysiological basis of generalized seizures termed ‘centrencephalic,’ in:The Physiopathogenesis of the Epilepsies(H. Gastaut, H. H. Jasper, J. Bancaud, and A. Waltregny, eds.), C. C. Thomas, Springfield, Illinois, pp. 209–236.
Gloor, P., 1977, The EEG and differential diagnosis of epilepsy, in:Current Concepts in Clinical Neurophysiology( H. Van Duijin, D. N.J. Donker, and A. C. van Huffelin, eds.), N. V. Drukkerij Trio, The Hague, pp. 9–21.
Gloor, P., Rasmussen, T., Garretson, H., and Maroun, F., 1964, Fractionized intracarotid metrazol injection. A new diagnostic method in electroencephalography, Electroencephalogr. Clin. Neurophysiol. 17:322–327.
Gloor, P., Quesney, L. F., and Zumstein, H., 1977, Pathophysiology of generalized penicillin epilepsy in the cat:The role of cortical and subcortical structures. II. Topical application of penicillin to the cerebral cortex and to subcortical structures, Electroencephalogr. Clin. Neurophysiol. 43:79–94.
Goddard, G. V., Mclntyre, D. C., and Leech, C. K., 1969, A permanent change in brain function resulting from daily electrical stimulation, Exp. Neurol. 25:295–330.
Goldring, S., 1972, The role of prefrontal cortex in grand mal convulsion, Arch. Neurol. 2:109–120.
Gordon, H. W., Bogen, J. E., and Sperry, R. W., 1971, Absence of deconnexion syndrome in two patients with partial section of the neocommissures, Brain 94:327–336.
Hassler, R., 1978, Interaction of reticular activating system for vigilance and the truncocephalic and pallical systems for directing awareness and attention under striatal control, in:Cerebral Correlates of Conscious Experience( P. A. Buser and A. Rougel-Buser, eds.), Elsevier/North- Holland, Amsterdam, pp. 111–129.
Hursh, J. B., 1949, Origin of the spike and wave pattern of petit mal epilepsy:An electroen- cephalographic study, Arch. Neurol. Psychiatry 53:274–282.
Jasper, H., and Droogleever-Fortuyn, L., 1947, Experimental studies on the functional anatomy of petit mal epilepsy, Res. Publ. Assoc. Res. Nerv. Ment. Dis. 26:272–298.
Jasper, H., and Kershman, J., 1941, Electroencephalographic classification of the epilepsies, Arch. Neurol. Psychiatry 45:903–943.
Jones, E. G., Coulter, J. D., Furton, H., and Porter, H., 1977, Cells of origin and terminal distribution of corticostriatal fibers arising in the sensory motor cortex of monkeys, J. Comp. Neurol. 173:53–80.
Kaneko, Y., Wada, J. A., and Kimura, H., 1981, Is the amygdaloid neuron necessary for amygdaloid kindling? in:Kindling 2( J. A. Wada, ed.), Raven Press, New York, pp. 249–264.
Kaplan, H. A., and Ford, D. H. (eds.), 1966, The Brain Vascular System, Elsevier, Amsterdam.
Karol, E. A., and Pandya, D. N., 1971, The distribution of the corpus callosum in the rhesus monkey, Brain 94:471–486.
Killam, K. F., Killam, E. K., and Naquet, R., 1967, An animal model of light sensitive epilepsy, Electroencephalogr. Clin. Neurophysiol. 22:497–513.
Kimura, H., Kaneko, Y., and Wada, J. A., 1981, Catecholamine and cholinergic systems and amygdaloid kindling, in:Kindling 2( J. A. Wada, ed.), Raven Press, New York, pp. 265–284.
Kopeloff, N., Kennard, M. A., Pacella, B. L., Kopeloff, L. M., and Chusid, J. G., 1950, Section of corpus callosum in experimental epilepsy in the monkey, Arch. Neurol. Psychiatry 63:719–729.
Kudo, T., Kudo, J., Yamauchi, T., and Yamashita, I., 1982, Experimental convulsion by penicillin:Role of cortical and subcortical structures, Abstract, 16th Annual Meeting of Japanese Epilepsy Society, Sapporo.
Künzle, H., 1975, Bilateral projections from precentral motor cortex to the putamen and other parts of the basal ganglia. An autoradiographic study in Macaca fascicularis, Brain Res. 88:195–209.
Künzle, H., 1978, An autogradiographic analysis of the efferent connections from the premotor and adjacent prefrontal regions in Macaca fasicularis, Brain Behav. Evol. 15:185–234.
Kusske, J. A., and Rush, J. L., 1978, Corpus callosum and propagation of afterdischarge to contralateral cortex and thalamus, Neurology 28:905–912.
Luessenhop, A. J., 1970, Interhemispheric commisurotomy as an alternate to hemispherectomy for control of intractable seizures, Am. Surg. 36:265.
Leussenhop, A. J., de la Cruz, T. P. C., and Fenichel, G. M., 1970, Surgical disconnection of the cerebral hemispheres for intractable seizures, J. Am. Med. Assoc. 213:1630.
Marcus, E. M., and Simon, S. A., 1968, An experimental model of some varieties of petit mal epilepsy. Electrical, behavioural correlations of acute bilateral epileptogenic foci in cerebral cortex, Epilepsia 9:233–248.
Marcus, E. M., and Watson, C. W., 1966, Bilateral synchronous spike and wave electrographic patterns in the cat. Interaction of bilateral cortical foci in the intact, bilateral cortico-callosal and adiencephalic preparation, Arch. Neurol. 14:601–610.
Marcus, E. M., and Watson, C. W., 1968, Symmetrical epileptogenic foci in monkey cerebral cortex. Mechanisms of interaction and regional variations in capacity for synchronous discharges, Arch. Neurol. 18:99–116.
Marcus, E. M., Watson, C. W., and Simon, S. A., 1968, Behavioral correlates of acute bilateral symmetrical epileptogenic foci in monkey cerebral cortex, Brain Res. 9:370–373.
McCaughran, J. A., Jr., Corcoran, M. E., and Wada, J. A., 1976, Development of kindled amygdaloid seizures after section of the forebrain commissure in rats, Folia Psychiatr. Neurol. Jpn.30:65–71.
McCaughran, J. A., Jr., Corcoran, M. E., and Wada, J. A., 1977, Facilitation of secondary site amygdaloid kindling following bisection of corpus callosum and hippocampal commissure in rats, Exp. Neurol. 57:132–141.
Mclntyre, D. C., 1975, Split brain rat:Transfer, interference of kindled amygdala convulsions, Can. J. Neurol. Sci. 2:429–437.
Mclntyre, D. C., and Goddard, G. V., 1973, Transfer, interference and spontaneous recovery of convulsions kindled from the rat amygdala, Electroencephalogr. Clin. Neurophysiol. 35:533–543.
Menini, C., 1976, Role du cortex frontal dans l’epilepsie photosensible du singe, Papio papio,J. Physiol. (Paris) 72:5–44.
Myers, R. E., 1965, Organization of visual pathway, in:Function in the Corpus Callosum( G. C. Ettlinger, ed.), J. and A. Churchill, London, pp. 133–143.
Musgrave, J., and Gloor, P., 1980, The role of the corpus callosum in bilateral interhemispheric synchrony of spike and wave discharge in feline generalized penicillin epilepsy, Epilepsia 21:369–378.
Mutani, R., 1980, The role of the corpus callosum in the interaction of multiple epileptogenic areas on neocortex, in:Advances in Epileptology:Xlth Epilepsy International Symposium( R. Ganger, R. Angeleri, and J. K. Penry, eds.), Raven Press, New York, 1–7.
Mutani, R., and Durelli, L., 1980, Mechanisms of interaction of asymmetrical bilateral epileptogenic foci in neocortex, Epilepsia 21:549–556.
Naquet, R., and Meldrum, B. S., 1972, Photogenic seizures in baboon, in:Experimental Models of Epilepsy:A Manual for the Laboratory Worker( D. D. Purpura, J. K. Penry, D. B. Tower, D. M. Woodbury, and R. D. Walter, eds.) Raven Press, New York, pp. 376–406.
Naquet, R., Menini, C., and Catier, J., 1973, Photically induced epilepsy in Papio papio. The initiation of discharges and the role of the frontal cortex and the corpus callosum, in:Synchronization of EEG Activity in the Epilepsies( H. Petsche and M. A. B. Brazier, eds.), Springer, New York, pp. 347–367.
Penfield, W., and Jasper, H. H., 1954, Epilepsy and the Functional Anatomy of the Human Brain, Little, Brown, Boston.
Pollen, D. A., 1964, Intracellular studies of cortical neurons during the thalamic induced wave and spike, Electroencephalogr. Clin. Neurophysiol. 17:398–404.
Pollen, D. A., and Sie, P. G., 1964, Analysis of thalamic induced wave and spike by modification in cortical excitability, Electroencephalogr. Clin. Neurophysiol. 17:154–163.
Pollen, D. A., Reid, K. H., and Perot, P., 1964, Microelectrode studies of experimental 3/sec wave and spike in the cat, Electroencephalogr. Clin. Neurophysiol. 17:57–67.
Quesney, L. F., and Gloor, P., 1978, Generalized penicillin in cat:Correlation between electro-physiological data and distribution of C-14 penicillin in the brain, Epilepsia 19:35–45.
Quesney, L. F., Gloor, P., Kratzenberg, E., and Zumstein, H., 1977, Pathophysiology of generalized penicillin epilepsy in the cat:The role of cortical and subcortical structures. I. Systemic application of penicillin, Electroencephalogr. Clin. Neurophysiol. 42:640–655.
Racine, R., Okujava, V., and Chipashivili, S., 1972, Modification of seizure activity by electrical stimulation. III. Mechanism, Electroencephalogr. Clin. Neurophysiol. 32:295–299.
Rodin, E., Onuma, T., Wasson, S., Poreack, J., and Rodin, M., 1971, Neurophysiological mechanisms involved in grand mal seizures induced by material and megimide, Electroencephalogr. Clin. Neurophysiol. 30:62–72.
Royce, G. J., 1982, Laminar origin of cortical neurons which projects upon the caudate nucleus:A horseradish peroxidase investigation in the cat, J. Comp. Neurol. 205:8–29.
Van Wagenen, W. P., and Herren, R. Y., 1940, Surgical division of commissural pathways in the corpus callosum, Arch. Neurol. Psychiatry 44:740–759.
Velasco, F., Velasco, M., Maldonado, H., Romo, R., and Estrada-Villanueva, F., 1979, Specific and nonspecific multiple unit activities during the onset of pentylenetetrazol seizures. III. Animals with ablations of the cerebral cortex. Epilepsia 20:635–642.
Wada, J. A., 1951, An experimental study on the neuronal mechanism of the spread of epileptic impulse, Folia Psychiatr. Neurol. Jpn. 4:289–294.
Wada, J. A., 1978, The clinical relevance of kindling:Species, brain site and seizure susceptibility, in:Limbic Mechanisms( D. E. Livingston and O. Hornykiewicz, eds.), Plenum Press, New York, pp. 369–388.
Wada, J. A., 1979, Epilepsy:Surgery may help when medication is ineffective, Br. Columbia Med. J. 21:150–153.
Wada, J. A., 1980, New surgical treatment through experimental models, in:Advances in Epileptology:Xth Epilepsy International Symposium( J. A. Wada and J. K. Penry, eds.), Raven Press, New York, pp. 195–204.
Wada, J. A., and Mizoguchi, T., 1984, Effect of forebrain bisection upon amygdaloid kindling in epileptic baboon, Papio papio, Epilepsia 25(3):278–287.
Wada, J. A., and Moyes, P. D., 1982, Anterior callosal bisection in medically refractory generalized seizure patients, Abstract, Joint Meeting of American EEG Society and American Epilepsy Society, Phoenix, November 12.
Wada, J. A., and Osawa, T., 1976, Spontaneous recurrent seizure state induced by daily electrical amygdaloid stimulation in Senegalese baboons, Papio papio, Neurology 26:273–286.
Wada, J. A., and Sato, M., 1975, Generalized convulsive seizure state induced by daily electrical stimulation of the amygdala in split brain cats, Epilepsia 16:417–130.
Wada, J. A., Terao, A., and Booker, H. E., 1972, Longitudinal correlative analysis of photosensitive baboons, Papio papio, Neurology 22:1272–1285.
Wada, J. A., Osawa, T., and Mizoguchi, T., 1975, Recurrent spontaneous seizure state induced by prefrontal kindling in Senegalese baboons, Papio papio, Can. J. Neurol. Sci. 2:501–508.
Wada, J. A., Mizoguchi, T., and Osawa, T., 1978, Secondarily generalized convulsive seizure induced by daily amygdaloid stimulation in rhesus monkeys, Neurology 28:1026–1036.
Wada, J. A., Mizoguchi, T., and Komai, S., 1981, Cortical motor activation in amygdaloid kindling:Observations in non-epileptogenic rhesus monkeys with anterior 2/3 callosal bisection, in:Kindling 2 ( J. A. Wada, ed.), Raven Press, New York, pp. 235–248.
Wada, J. A., Nakashima, T., and Kaneko, Y., 1982, Forebrain bisection and feline amygdaloid kindling, Epilepsia 23:521–531.
Walker, A. E., 1969, The generalization of seizures from a focal discharge, in:The Physiopatho- genesis of the Epilepsies( H. Gastaut, H. H. Jasper, J. Bancaud, and A. Waltregny, eds.), C. C. Thomas, Springfield, Illinois, pp. 237–248.
Weir, B., 1964, Spike-wave form stimulation of reticular core, Arch. Neurol. 11:209–218.
Weir, B., 1965, The morphology of the spike-wave complex, Electroencephalogr. Clin. Neurophysiol. 19:284–290.
Weir, B., and Sie, P. G., 1966, Extracellular unit activity in cat cortex during the spike and wave complex, Epilepsia 7:3–43.
Wilson, D. H., Culver, C., Waddington, M., and Gazzaniga, M., 1975, Disconnection of the cerebral hemisphere:An alternative to hemispherectomy of intractable seizures, Neurology 25:1149–1153.
Wilson, D. H., Reeves, A. G., Gazzaniga, M., and Culver, C., 1977, Cerebral commissurotomy for control of intractable seizures, Neurology 27:708–715.
Wilson, D. H., Reeves, A. G., and Gazzaniga, M., 1978, Division of corpus callosum for uncontrollable epilepsy, Neurology 28:649–653.
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Wada, J.A., Komai, S. (1985). Effect of Anterior Two- Thirds Callosal Bisection Upon Bisymmetrical and Bisynchronous Generalized Convulsions Kindled from Amygdala in Epileptic Baboon, Papio papio. In: Reeves, A.G. (eds) Epilepsy and the Corpus Callosum. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2419-5_5
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