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Chromosomal Disorders in Pregnancy

  • Chapter
Principles of Medical Therapy in Pregnancy

Abstract

Approximately 1:160 liveborns has an abnormality in chromosome number or structure. Some chromosome abnormalities (e.g., trisomy 13 or 18) are so deleterious that they preclude reproduction by an affected individual. Other chromosomal anomalies (e.g., Down’s syndrome or 47,XXX) are less severe, and pregnancy is not unexpected. Individuals with the latter anomalies usually do not have consistent physiological or structural abnormalities that impinge on pregnancy; the primary problem with such pregnancies is the increased frequency of chromosomally abnormal offspring. This increased risk is the subject of this chapter.

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Authors
  1. Marion S. Verp
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Editors and Affiliations

  1. Rush Medical College, Chicago, Illinois, USA

    Norbert Gleicher M.D. (Professor of Obstetrics and Gynecology and Assistant Professor of Immunology/Microbiology, Chairman) (Professor of Obstetrics and Gynecology and Assistant Professor of Immunology/Microbiology, Chairman)

  2. Department of Obstetrics and Gynecology, Mount Sinai Hospital Medical Center, Chicago, Illinois, USA

    Norbert Gleicher M.D. (Professor of Obstetrics and Gynecology and Assistant Professor of Immunology/Microbiology, Chairman) (Professor of Obstetrics and Gynecology and Assistant Professor of Immunology/Microbiology, Chairman)

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© 1985 Plenum Publishing Corporation

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Verp, M.S. (1985). Chromosomal Disorders in Pregnancy. In: Gleicher, N. (eds) Principles of Medical Therapy in Pregnancy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2415-7_190

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  • DOI: https://doi.org/10.1007/978-1-4613-2415-7_190

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9471-9

  • Online ISBN: 978-1-4613-2415-7

  • eBook Packages: Springer Book Archive

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