Chromosomal Disorders in Pregnancy

  • Marion S. Verp


Approximately 1:160 liveborns has an abnormality in chromosome number or structure. Some chromosome abnormalities (e.g., trisomy 13 or 18) are so deleterious that they preclude reproduction by an affected individual. Other chromosomal anomalies (e.g., Down’s syndrome or 47,XXX) are less severe, and pregnancy is not unexpected. Individuals with the latter anomalies usually do not have consistent physiological or structural abnormalities that impinge on pregnancy; the primary problem with such pregnancies is the increased frequency of chromosomally abnormal offspring. This increased risk is the subject of this chapter.


Down Syndrome Turner Syndrome Premature Ovarian Failure Gonadal Dysgenesis Abnormal Cell Line 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Publishing Corporation 1985

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  • Marion S. Verp

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