Disorders of Bone Marrow

  • Sue M. Palmer
  • John C. Morrison

Abstract

Disorders of the bone marrow are a rare occurrence in the practice of obstetrics and gynecology. However, once failure of the multipotential hematopoietic stem cell occurs, the resulting pancytopenia (anemia, neutropenia, and thromtocytopenia) is devastating. A hypocellular bone marrow with fatty degenerative changes is called aplastic anemia.1,2 On the other hand, the rare selective aplasia of the erythropoietic cell line is designated as pure red blood cell aplasia. When the bone marrow is replaced with either tumor or granulomatous changes, myelophthistic anemia is the diagnosis. Finally, paroxysmal nocturnal hemoglobinuria is thought to be caused by the bone marrow production of an abnormal clone of defective red cells, platelets, and granulocytes.

Keywords

Hepatitis Tuberculosis Pancreatitis Testosterone Folic Acid 

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References

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    Erslev AJ: Erythrocyte disorders—anemas related to disturbance of stem cell proliferation or differentiation, in Williams WJ, Beuttler E, Erslev AJ et al (eds): Hematology, ed 2. New York, McGraw-Hill, 1977, pp 258–299Google Scholar
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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Sue M. Palmer
  • John C. Morrison

There are no affiliations available

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