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Part of the book series: Methodological Surveys in Biochemistry and Analysis ((ANAY,volume 14))

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Abstract

The use of isotope-labelled drugs as internal standards, or to elucidate some analytical problem, is a very powerful technique. The approach is often quicker and easier than alternative methods and sometimes is the only solution to the problem. Chromatographic separation followed by mass spectrographs (MS) detection of test and isotopic labelled materials is generally considered to be the definitive analytical technique but is not without its difficulties and pitfalls.

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© 1984 Plenum Press, New York

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Whelpton, R. (1984). Isotope-Labelled Materials as Internal Standards. In: Reid, E., Wilson, I.D. (eds) Drug Determination in Therapeutic and Forensic Contexts. Methodological Surveys in Biochemistry and Analysis, vol 14. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2397-6_4

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  • DOI: https://doi.org/10.1007/978-1-4613-2397-6_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9462-7

  • Online ISBN: 978-1-4613-2397-6

  • eBook Packages: Springer Book Archive

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