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Biological Applications

  • Chapter
Dynamic Light Scattering

Abstract

In 1964, Pecora(1) showed theoretically the utility of quasielastic light scattering (QLS) for characterizing the translational, rotational, and internal dynamics of polymer chains. In 1967, the theory was brought to experimental realization in two quite different types of biological systems. Benedek and co-workers(2) used QLS to measure translational diffusion coefficients of proteins and nucleic acids, and Berge et al (3) measured the motility of spermatozoa. These two types of biological applications—macromolecular characterization and physiological analysis—have both developed enormously since the late 1960s, but the major themes emerged early.

Portions of this chapter are reprinted with permission from the Annual Review of Bio-physics and Bioengineering, Vol. 10. © 1981 by Annual Review Inc.

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Bloomfield, V.A. (1985). Biological Applications. In: Pecora, R. (eds) Dynamic Light Scattering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2389-1_10

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