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General Principles of Analytical Mass Spectrometry

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Book cover Mass Spectrometry in Environmental Sciences

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Abstract

The purpose of this introductory chapter is to set the stage for what is to follow. Clearly, it is not possible to give a complete account of all the features of a modern mass spectrometer in a few pages. Accordingly, we shall concentrate on establishing some essential principles, give references to sources of more detailed information, and try to give some indication of more modern trends in instrumentation. Some of these trends will be fully described in later chapters in this book and thus will be treated sketchily here.

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Reference

  1. J. H. Beynon, Mass Spectrometry and its Applications to Organic Chemistry, Elsevier, Amsterdam, 1960.

    Google Scholar 

  2. W. H. McFadden, Techniques of Combined GC/MS: Applications in Organic Analysis, Wiley, New York, 1973.

    Google Scholar 

  3. F. W. McLafferty, Interpretation of Mass Spectra, 3rd ed., University Science Books, Mill Valley, CA, 1980.

    Google Scholar 

  4. A. L. Burlingame, B. J. Kimble, and P. J. Derrick, Anal. Chem. 48, 368R–403R (1976).

    Article  Google Scholar 

  5. A. L. Burlingame, C. H. L. Shackleton, I. Howe, and O. S. Chizhov, Anal. Chem. 50, 346R–384R (1978).

    Article  Google Scholar 

  6. A. L. Burlingame, T. A. Baillie, P. J. Derrick, and O. S. Chizhov, Anal. Chem.52, 214R–258R (1980).

    Article  Google Scholar 

  7. D. H. Williams, Specialist Periodical Report: Mass Spectrometry, Vol. 1, The Chemical Society, London, 1971.

    Google Scholar 

  8. D. H. Williams, Specialist Periodical Report: Mass Spectrometry, Vol. 2, The Chemical Society, London, 1973.

    Google Scholar 

  9. R. A. W. Johnstone, Specialist Periodical Report: Mass Spectrometry, Vol. 3, The Chemical Society, London, 1975.

    Google Scholar 

  10. R. A. W. Johnstone, Specialist Periodical Report: Mass Spectrometry, Vol. 4, The Chemical Society, London, 1977.

    Google Scholar 

  11. R. A. W. Johnstone, Specialist Periodical Report: Mass Spectrometry, Vol. 5, The Chemical Society, London, 1979.

    Google Scholar 

  12. M. L. Gross (ed.), High Performance Mass Spectrometry: Chemical Applications, ACS Symposium Series, 70, American Chemical Society, Washington, D. C., 1978.

    Google Scholar 

  13. D. H. Williams and I. Howe, Principles of Organic Mass Spectrometry, McGraw-Hill, London, 1972.

    Google Scholar 

  14. K. Levsen, Fundamental Aspects of Organic Mass Spectrometry, Verlag Chemie, Weinheim, 1978.

    Google Scholar 

  15. R. D. Craig, R. H. Bateman, B. N. Green and D. S. Millington, Phil. Trans. Roy. Soc. A293, 135 – 155 (1979).

    Google Scholar 

  16. L. Ramaley, M. E. Nearing, W. D. Jamieson, and R. G. Ackman, Proceedings of the 29th Annual Conference on Mass Spectrometry and Allied Topics, Paper MPB8, American Society of Mass Spectrometry, 1981.

    Google Scholar 

  17. G. W. A. Milne and M. J. Lacey, in CRC Critical Reviews in Analytical Chemistry, Vol. 4, CRC Press, Cleveland, 1974, pp. 45 – 104.

    Google Scholar 

  18. W. J. Richter and H. Schwarz, Angew. Chem. Int. Ed. Engl 17, 424 – 439 (1978).

    Article  Google Scholar 

  19. K. R. Jennings, in High Performance Mass Spectrometry: Chemical Application, (M. L. Gross, ed.), ACS Symposium Series, American Chemical Society, Washington, D.C., 1978, pp. 179 – 187.

    Google Scholar 

  20. H.R. Schulten, Int. J. Mass Spectrom. Ion Phys. 32, 97 – 283 1979.

    Article  CAS  Google Scholar 

  21. T. Matsuo, H. Matsuda, and I. Katakuse, Anal Chem. 51, 1329 – 1331 (1979).

    Article  CAS  Google Scholar 

  22. K. M. Straub and A. L. Burlingame, in Advances in Mass Spectrometry, Vol. 8, (A. Quayle, ed.), Institute of Petroleum, London, 1980, pp. 1127 – 1134.

    Google Scholar 

  23. K. F. I. Heinrich and D. E. Newbury, Secondary Ion Mass Spectrometry, NBS Special publication No. 427, U.S. Dept. of Commerce, Washington, D.C., 1975.

    Google Scholar 

  24. M. Barber, R. S. Bardoli, R. D. Sedgwick, and A. N. Tyler, J. Chem. Soc. Chem. Commun., pp. 325 – 327 (1981).

    Google Scholar 

  25. M. A. Baldwin and F. W. McLafferty, Org. Mass Spectrom. 7, 1353 – 1356 (1973).

    Article  CAS  Google Scholar 

  26. G. Hansen and B. Munson, Anal. Chem. 50, 1130 – 1134 (1978).

    Article  CAS  Google Scholar 

  27. D. I. Carroll, I. Dzidic, M. G. Horning, F. E. Montgomery. G. Nowlin, R. N. Stillwell, J-P. Thenot, and E. C. Horning, Anal. Chem. 51, 1858 – 1860 (1979).

    Article  CAS  Google Scholar 

  28. R. C. Dougherty and C. R. Weisenberger, J. Am. Chem. Soc. 90, 6570 – 6571 (1968).

    Article  CAS  Google Scholar 

  29. R. C. Dougherty, J. D. Roberts, and F. J. Biros, Anal. Chem. 47, 49 – 54 (1975).

    Article  Google Scholar 

  30. K. R.Jennings, Phil Trans. Roy. Soc. A293, 125 – 133 (1979).

    Google Scholar 

  31. R. D. MacFarlane, in Biochemical Applications of Mass Spectrometry (G. R. Waller and O. C. Dermer, eds.), Wiley, New York, 1980, pp. 1209 – 1218.

    Google Scholar 

  32. J. E. Campana, Int. J. Mass Spectrom. Ion Phys. 33, 101 – 117 (1980).

    Google Scholar 

  33. J. F. J. Todd, in Dynamic Mass Spectrometry, Vol. 4, (D. Price and J. F. J. Todd, eds.), Heyden, London, 1976, pp. 11 – 24.

    Google Scholar 

  34. D. Dixon, in Dynamic Mass Spectrometry, Vol. 4, (D. Price and J. F. J. Todd, eds.), Heyden, London, 1976, pp. 83 – 98.

    Google Scholar 

  35. D. F. Hunt, G. C. Stafford, Jr., F. W. Crow, and J. W. Russell, Anal Chem. 48, 2098 – 2105 (1976)

    Article  CAS  Google Scholar 

  36. H. E. Duckworth and S. N. Ghoshal, in Mass Spectrometry, (C. A. McDowell, ed.), McGraw-Hill, New York, 1968, pp. 201 – 274.

    Google Scholar 

  37. W. G. Cross, Rev. Sci. Instrum. 22, 717 – 722 (1951).

    Article  Google Scholar 

  38. M. B. Comisarow and A. G. Marshall, Canad.J. Chem. 52, 1997 – 1999 (1974).

    Article  CAS  Google Scholar 

  39. C. L. Wilkins, Anal. Chem. 50, 493A–500A (1978).

    Article  Google Scholar 

  40. R. L. Hunter and R. T. Mclver, Anal. Chem. 51, 699 – 704 (1979).

    Article  CAS  Google Scholar 

  41. P. A. Leclercq, G.J. Scherpenzeel, and C. A. Cramers, Proceedings of the 29th Annual Conference Mass Spectrometry and Allied Topics, Paper MPMOA3. American Society Mass Spectrometry, 1981.

    Google Scholar 

  42. J. P. Lehman and E. J. Younginger, Int. J. Mass Spectrom. Ion Phys. 33, 95 – 98 (1980).

    Article  CAS  Google Scholar 

  43. J. A. Browder, R. L. Miller, W. A. Thomas, and G. Sanzone, Int. J. Mass Spectrom. Ion Phys. 37, 99 – 108 (1981).

    Article  CAS  Google Scholar 

  44. B. A. Mamyrin, V. I. Karataev, D. V. Shmikk, and V. A. Zagulin, Soviet PhysicsJ.E.T.P. 37, 45 – 48 (1973).

    Google Scholar 

  45. E. A. Kurz, Am. Lab. (March, 1979 ).

    Google Scholar 

  46. J. L. Wiza, Nucl. Instrum. Methods 162, 587 – 601 (1979).

    Google Scholar 

  47. C. E. Giffin, H. G. Boettger, and D. D. Norris, Int. J. Mass Spectrom. Ion Phys. 15, 437 – 449 (1974).

    Article  CAS  Google Scholar 

  48. J. H. Beynon, D. O. Jones, and R. G. Cooks, Anal. Chem. 47, 1734 – 1738 (1975).

    Article  CAS  Google Scholar 

  49. J. R. Chapman, Computers in Mass Spectrometry, Academic, London, 1978.

    Google Scholar 

  50. S. J. Gaskell and D. S. Millington, Biomed. Mass Spectrom. 5, 557 – 558 (1978).

    CAS  Google Scholar 

  51. R. W. Kondrat and R. G. Cooks, Anal. Chem. 50, 81A–92A (1978).

    Article  Google Scholar 

  52. F. W. McLafferty, in ( C. R. Waller and O. C. Dermer, eds.), Biochemical Applications of Mass Spectrometry, Wiley, New York, 1980, pp. 1159 – 1168.

    Google Scholar 

  53. F. W. McLafferty, Canad.J. Chem. 13, 33 – 38 (1980).

    CAS  Google Scholar 

  54. J. H. Beynon, R. G. Cooks, J. W. Amy, W. E. Baitinger, and T. Y. Ridley, Anal. Chem. 45, 1023A–1031A (1973).

    Google Scholar 

  55. T. Ast, M. H. Bozorgzadeh, J. L. Wiebers, J. H. Beynon, and A. G. Brenton, Org. Mass Spectrom.14, 313 – 318 (1979).

    Article  CAS  Google Scholar 

  56. R. K. Boyd and J. H. Beynon, Org. Mass Spectrom. 12, 163 – 165 (1977).

    Article  CAS  Google Scholar 

  57. R. K. Boyd and B. Shushan, Anal. Chem. 53, 421 – 427 (1980).

    Google Scholar 

  58. S. C. Gates, N. Dendramis, and C. C. Sweeley, Clin. Chem. 24, 1674 – 1679 (1978).

    CAS  Google Scholar 

  59. B.J. Millard, Quantitative Mass Spectrometry, Heyden, Lond, 1978.

    Google Scholar 

  60. A. P. DeLeenheer and A. Cruyl, in Biochemical Applications of Mass Spectrometry(G. R. Waller and O. C. Dermer, eds.), Wiley, New York, 1980, pp. 1169 – 1207.

    Google Scholar 

  61. W. F. Haddon and H. C. Lukens, Proceedings of the 22nd Conference on Mass Spectrometry and Allied Topics, American Society Mass Spectrometry, 1974, pp. 436 – 439.

    Google Scholar 

  62. D. F. Hunt, G. C. Stafford, J. Shabanowitz, and F. W. Crow, Anal. Chem. 49, 1884 (1977)

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Chemistry, University of Guelph, Guelph, Ontario, N1G 2W1, Canada

    R. K. Boyd

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  1. R. K. Boyd
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Editor information

Editors and Affiliations

  1. University of Waterloo, Waterloo, Ontario, Canada

    F. W. Karasek

  2. University of Bayreuth, Bayreuth, Germany

    O. Hutzinger

  3. University of Guelph, Guelph, Ontario, Canada

    S. Safe

  4. Texas A&M University, College Station, Texas, USA

    S. Safe

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© 1985 Plenum Press, New York

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Boyd, R.K. (1985). General Principles of Analytical Mass Spectrometry. In: Karasek, F.W., Hutzinger, O., Safe, S. (eds) Mass Spectrometry in Environmental Sciences. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2361-7_1

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  • DOI: https://doi.org/10.1007/978-1-4613-2361-7_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9445-0

  • Online ISBN: 978-1-4613-2361-7

  • eBook Packages: Springer Book Archive

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