The use of psychotropic medications in the treatment of cancer
This chapter will focus on the use of psychotropic medication to treat depression, anxiety, and acute confusion and agitation. Psychotropic medications are almost certainly underused in patients with cancer. A frequent lack of appreciation of the patient’s level of emotional distress, particularly depression , coupled with a certain therapeutic nihilism, may account for this lack of vigor in an area where the physician actually stands a good chance of helping the patient. Psychotropic drug use in seriously ill patients requires special care. The presence of significant cardiac, pulmonary, hepatic, renal, gastrointestinal, or endocrinologic disease may create specific pharmacologic dilemmas. The discussion of psychotropic drug use in cancer patients which follows is, by necessity, selective. Any reader wishing a more comprehensive discussion of these specific situations is referred to several excellent reviews [2–5].
KeywordsPsychotropic Medication Antipsychotic Medication Antidepressant Medication Target Dose Extrapyramidal Side Effect
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- 2.Risch SC, Groom GP, Janowsky DS. 1981. Interfaces of psychopharmacology and cardiology — Part one. J Clin Psych 42:23–34.Google Scholar
- 3.Risch SC, Groom GP, Janowsky DS. 1981. Interfaces of psychopharmacology and cardiology — Part two. J Clin Psych 42:42–59.Google Scholar
- 4.Hershey SC, Hales RE. 1984. Psychopharmacologic approach to the medically ill patient. Psych Clin North Am 7:803–816.Google Scholar
- 5.Siris SG, Rifkin A. 1981. The problem of psychopharmacology in the medically ill. Psych Clin North Am 4:379–390.Google Scholar
- 8.Goldberg RJ, Mor V. 1905. A survey of psychotropic use in terminal cancer patients. Psychosomatics 26:746–748.Google Scholar
- 12.Shader RI, Greenblatt DJ. 1977. Clinical implications of benzodiazepine pharmacokinetics. Am J Psych 134:652–656.Google Scholar
- 17.Silberfarb PM, Philibert D, Levine PM. 1980. Psychological aspects of neoplastic disease: II. Affective and cognitive effects of chemotherapy in cancer patients. Am J Psych 137:597–601.Google Scholar
- 18.Shapiro WR. 1976. Remote effects of neoplasm on the central nervous system: Encephalopathy. In: Advances in Neurology, Vol. 15 Thompson RA, Green JR (eds), pp 101–117.Google Scholar