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Hematologic disorders associated with cancer: II. White blood cell disorders

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Issues in Supportive Care of Cancer Patients

Part of the book series: Cancer Treatment and Research ((CTAR,volume 30))

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Abstract

White blood cell disorders that occur in patients with cancer include both quantitative and qualitative abnormalities. Many of the abnormalities of the white blood cell compartment are relatively benign and do not require treatment. These disturbances frequently are poorly understood in terms of etiology, sometimes waxing and waning with the disease process itself. The various interactions between the cancer and the white blood cell compartment remain to be elucidated.

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References

  1. Robinson WA. 1974. Granulocytosis in neoplasia. Ann NY Acad Sci 230:212–218.

    Article  CAS  PubMed  Google Scholar 

  2. Sato N et al. 1979. Granulocytosis and colony-stimulating activity (CSA) produced by a human squamous cell carcinoma. Cancer 43:605–610.

    Article  CAS  PubMed  Google Scholar 

  3. Suda T et al. 1980. A case of lung cancer associated with granulocytosis and production of colony-stimulating activity by the tumor. Br J Cancer 41:980–984.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  4. Kimura N, Niho Y, Yanase T. 1982. A high level of colony-stimulating activity in a lung cancer patient with extensive leukocytosis, and the establishment of a CSA procucing cell line (KONT). Scand J Haematol 28:417–424.

    Article  CAS  PubMed  Google Scholar 

  5. Bockman RS, Bellin A, Repo MA, Hickok NJ, Kameya T. 1983. In vivo and in vitro biological activities of two human cell lines derived from anaplastic lung cancers. Cancer Res 43:4571–4576.

    Google Scholar 

  6. Okabe T et al. 1984. Establishment of a human colony-stimulating factor-producing cell line from an undifferentiated large cell carcinoma of the lung. Cancer 54:1024–1029.

    Article  CAS  PubMed  Google Scholar 

  7. Lee MA, Lottsfeldt JL. 1984. Augmentation of neutrophilic granulocyte progenitors in the bone marrow of mice with tumor induced neutrophilia: Cytochemical study of in vitro colonies. Blood 64:499–506.

    CAS  PubMed  Google Scholar 

  8. Takeda A et al. 1904. Clear cell carcinoma of the ovary with colony-stimulating-factor production. Cancer 54:1019–1023.

    Article  Google Scholar 

  9. Burgess AW, Metealf D. 1980. The nature and action of granulocyte-macrophage colony-stimulating factors. Blood 56:947–958.

    CAS  PubMed  Google Scholar 

  10. Barrett O. 1970. Monocytosis in malignant disease. Ann Intern Med 73:991–992.

    Article  PubMed  Google Scholar 

  11. Kaplan HS. 1980. Hodgkin’s disease, second edition. Harvard University press, Cambridge MA.

    Google Scholar 

  12. Zittoun R. 1976. Subacute and chronic myelomonocytic leukemia: a distinct haematologic entity. Br J Haematol 32:1–5.

    Article  CAS  PubMed  Google Scholar 

  13. Warnke RA, Kim H, Dorfman RF. 1975. Malignant histiocytosis (histiocytic medullary reticulosis); Clinicopathalogic study of 29 cases. Cancer 35:215–230.

    Article  CAS  PubMed  Google Scholar 

  14. Gibson A. 1946. Monocytic leukemoid reaction associated with tuberculosis and a mediastinal teratoma. J Pathol Bacteriol 58:469–474.

    Article  CAS  PubMed  Google Scholar 

  15. Rotman M, Ansley H, Togow L, Stowe S. 1977. Monocytosis a new observation during radiotherapy. Int. J Rad Oncol Biol Phys 2:117–121.

    Article  CAS  Google Scholar 

  16. Underwood JCE. 1974. Lymphoreticular infiltration in human tumors: prognositc and biological implications: a review. Br J Cancer 30:538–548.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  17. Lauder I, Aherne W, Stewart J, Sainsbury R. 1977. Macrophage infiltration of breast tumors: a prospective study. J Clin Pathol 30:563–568.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  18. Luebbers EL et al. 1977. Heterogeneity and prognostic significance of breast tumors: A prospective study. J Clin Pathol 30:563–568.

    Article  Google Scholar 

  19. Lowe D, Jorizzo J, Hütt MSR. 1981. Tumor-associated eosinophilia; a review. J Clin Pathol. 34:1343–1348.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  20. Kodama T et al. 1984. Large cell carcinoma of the lung associated with marked eosinophilia. Cancer 54:2313–2317.

    Article  CAS  PubMed  Google Scholar 

  21. Reddy Sethu KS, Hyland RH, Alison RE, Sturgeon JFG, Hutcheon MA. 1984. Tumor-associated peripheral eosinophilia: two unusual cases. J. Clin Oncol 2:1165–1169.

    Google Scholar 

  22. Goetzl EJ et al. 1978. Production of a low molecular weight eosinophil polymorphonuclear leukocyte chemotactic factor by anaplastic squamous cell carcinoma of human lung. J Clin Invest 61:770–780.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  23. Wasserman S et al. 1979. Tumor associated eosinophilotactic factor. N Engl J Med 290:420–424.

    Article  Google Scholar 

  24. Goetzl EJ et al. 1980. A novel eosinophil chemotactic factor derived from a histiocytic lymphoma of the central nervous system. Clin Exp Immunol 40:249–255.

    CAS  PubMed Central  PubMed  Google Scholar 

  25. Muggia EM, Ghossein NA, Wohl H. 1973. Eosinophilia following radiation therapy. Oncology 27:118–127.

    Article  CAS  PubMed  Google Scholar 

  26. Rosenthal S, Schwartz JH, Canellos GP. 1977. Basophilia chronic granulocytic leukemia with hyperhistaminaemia. Br J Haematol 36:367–372.

    Article  CAS  PubMed  Google Scholar 

  27. Pandolfi F et al. 1984. Classification of patients with T cell chronic lymphocytic leukemia and expansion of granulai lymphocytes: heterogeneity of Italian cases by a multiparameter analysis. J Clin Immunol 4:174–184.

    Article  CAS  PubMed  Google Scholar 

  28. Lotzova E. 1984. The role of natural killer cells in immune surveillance against malignancies. Cancer Bull 36:215–225.

    Google Scholar 

  29. Semenzato G et al. 1984. Abnormal expansions of polyclonal large to small size granular lymphocytes: reactive or neoplastic process? Blood 63:1271–1278.

    CAS  PubMed  Google Scholar 

  30. Taylor HG, Terebelo HR, Gameza. 1982. Lymphocytosis in a patient with malignant fibrous histiocytoma. Cancer 50:1563–1567.

    Article  CAS  PubMed  Google Scholar 

  31. Gavarotti P, Boccadara M, Redoglia V, Golzio F, Pileri A. 1985. Reactive plasmacytosis. Case report and review of the literature. Acta Haematol 73:108–110.

    Article  CAS  PubMed  Google Scholar 

  32. Kyle RA. 1978. Monoclonal gammopathies of undetermined significance: natural history of 241 cases. Am J Med 64:814–826.

    Article  CAS  PubMed  Google Scholar 

  33. Isobe T, Osserman EF. 1975. Pathologic conditions associated with plasma cell dyscrasias: a study of 806 cases. Ann NY Acad Sci 190:507–512.

    Article  Google Scholar 

  34. Hoagland HC. 1982. Hematologic complications of cancer chemotherapy. Sem Oncol 9:95–101.

    CAS  Google Scholar 

  35. Olofsson T, Olsson I. 1980. Biochemical characterization of a leukemia-associated inhibitor (LAI) suppressing normal granulopoiesis in vitro. Blood 55:983–991.

    CAS  PubMed  Google Scholar 

  36. Bognacki J, Broxmeyer HE, Lobue J: 1981. Isolation and biochemical characterization of leukemia-associated inhibitory activity that suppresses colony and cluster formation of cells. Biochem. Biophys. Acta 672:176–190.

    Article  CAS  PubMed  Google Scholar 

  37. Olsson I, Olofsson T. 1985. Production characteristics and mode of action of hemopoietic growth inhibitors in myeloid leukemias (editorial). Med. Oncol Tumor Pharmacother 2:1–6.

    CAS  PubMed  Google Scholar 

  38. Vaudaux P et al. 1984. Adriamycin impairs phagocytic function and induces morphologic alterations in human neutrophils. Cancer 54:400–410.

    Article  CAS  PubMed  Google Scholar 

  39. Matamoros MC, Walker BK, Van Dyke K, Van Dyke CJ. 1983. Effect of cancer chemotherapeutic agents on the chemiluminescence of human granulocytes. Pharmacol 27:29–39.

    Article  CAS  Google Scholar 

  40. Samak R, Edelstein R, Bogucki D, Samak M, Israel L. 1980. Testing the monocyte-macrophage system in human cancer. Biomedicine 32:165–169.

    CAS  PubMed  Google Scholar 

  41. Boetchu DA, Leonard EJ. 1974. Abnormal monocyte chemotactic response in cancer patients. J Natl Cancer Inst 52:1091–1099.

    Google Scholar 

  42. Snyderman R, Pike MC. 1976. An inhibitor of macrophage Chemotaxis produced by neoplasms. Science 192:370–372.

    Article  CAS  PubMed  Google Scholar 

  43. DeYoung NJ, Gill PG. 1984. Monocyte antibody-dependent cellular cytotoxicity in cancer patients. Cancer Immunol. Immunother 18:54–58.

    Article  CAS  Google Scholar 

  44. Balm FAJM et al. 1984. Monocuclear phagocyte function in head and neck cancer. Cancer 54:1010–1015.

    Article  CAS  PubMed  Google Scholar 

  45. Romagnani S, Ferrini PLR, Ricci M. 1985. The immune derangement in Hodgkin’s disease. Sem Hematol 22:41–55.

    CAS  Google Scholar 

  46. Watanobe T et al. 1985. T cell subsets in patients with gastric cancer. Oncology 42:89–91.

    Article  Google Scholar 

  47. Hayashi Y et al. 1984. Peripheral T gamma lymphocyte population in head and neck cancer. Cancer Immunol. Immunother 17:160–164.

    Article  CAS  PubMed  Google Scholar 

  48. McCluskey DR, Roy AD, Abram WP, Martin WMC. 1983. T Lymphocyte subsets in the peripheral blood of patients with benign and malignant breast disease. Br J Cancer 47:307–309.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

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Authors
  1. Jo-Anne M. Bessette
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Editors and Affiliations

  1. Baystate Medical Center, Springfield, MA, 01199, USA

    Donald J. Higby M.D. (Chief Hematology/Oncology Service) (Chief Hematology/Oncology Service)

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© 1986 Martinus Nijhoff Publishers, Boston

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Bessette, JA.M. (1986). Hematologic disorders associated with cancer: II. White blood cell disorders. In: Higby, D.J. (eds) Issues in Supportive Care of Cancer Patients. Cancer Treatment and Research, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2325-9_2

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  • DOI: https://doi.org/10.1007/978-1-4613-2325-9_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9429-0

  • Online ISBN: 978-1-4613-2325-9

  • eBook Packages: Springer Book Archive

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