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Interactions Among the Nervous, Endocrine and Immune Systems (Nim)

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Neuroregulation of Autonomic, Endocrine and Immune Systems

Part of the book series: Topics in the Neurosciences ((TNSC,volume 2))

Abstract

Almost every known endocrine substance directly affects both the nervous and immune systems. This is true also of many neurally-active polypeptides and other neurotransmitters and neuromodulators. Thus, there is a constant interaction between the nervous and immune systems in all vertebrates, and probably in all invertebrates, although many immunologists would deny the existence of an “immune” system in invertebrates. In fact, all animals have a host-defense system and even unicellular animals exhibit reflex reactions and other complex behaviors, although they do not have multi-cellular nervous systems.

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References

  1. Ader, R. Ed., 1980, Psychoneuroimmunology. Academic, New York.

    Google Scholar 

  2. Ader, R. and Cohen, N., 1975, Behaviorally conditioned immunosuppression, in Psychosom. Med. 37(4), 333–340.

    PubMed  CAS  Google Scholar 

  3. Baciu, I., 1946, The Role of the Central Nervous System in the Inducement of the Phagocytic Reaction. Doctoral dissertation, Institute of Physiology and Medical Physics, University of Cluj ( Romanian: English translation available).

    Google Scholar 

  4. Baciu, I., Olteanu, A., Prodan, T., Baiescu, M., and Vaida, A. Changes of Phagocytic Biological Rhythm by Reproduction of Circadian Times and by Influences upon Hypothalamus, in Neuroimmunomodulation (Proceedings of First International Workshop on NIM), IWGN, Bethesda, 1985.

    Google Scholar 

  5. Benatato, Gr., Vitebski, V., Neumann, E., Budai, R., 1956, Contritutii noi la studiul mecanismului neuro-umoral de reglare a proceselor imunobiologice. Bulletin stiintific Acad. R.P.R., 8, 327–337, (Romanian).

    Google Scholar 

  6. Bulloch, K., 1985, Neuroanatomy of lymphoid tissue: a review, in Neural Modulation of Immunity, Guillemin, R., Cohn, M. and Melnechuk, T. eds. Raven Press, N.Y., pp. 111–141.

    Google Scholar 

  7. Cooper, E.L., Ed. Stress, Immunity and Aging, Marcel Dekker, N.Y., 1984.

    Google Scholar 

  8. Devoino, L.V. and Morozova, N.B., 1985, Serotonergic System in Neuroimmunomodulation:Intraimmune Mechanisms and Mechanisms of Inhibition, in Neuroimmunomodulation: (Proceedings of the First International Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  9. Draskoci, M., and Jankovic, B.D., 1964, Involution of thymus and suppression of immune response in rats treated with reserpine, Nature, 202: 408.

    Article  PubMed  CAS  Google Scholar 

  10. Fabris, N., Garaci, E., Hadden, J., and Mitchison, N., Eds., 1983, Immunomodulation. Plenum, N.Y.

    Google Scholar 

  11. Fontana, A., Bodmer, St., Borbely, A., Fierz, W., Frei, K., Schnyder, B., Schwyzer, M., Tobler, J., and de Tribolet, N., 1985, Astrocytes: a study of their involvement in T-Cell activation, fever and sleep in Neuroimmunomodulation: (Proceedings of the First International Workshop on NIM. IWGN, Bethesda.

    Google Scholar 

  12. Fox, B.H. and Newberry, B.H. Impact of Psychoneuroendocrine Systems in Cancer and Immunity. Lewiston, N.Y. Hogrefe, 1984.

    Google Scholar 

  13. Geschwind, N. and Behan, P.O., 1985, Left-handedness and dyslexia: immune and endocrine associations. In Neuroimmunomodulation (Proceedings of the First International Workshop on NIM. IWGN, Bethesda.

    Google Scholar 

  14. Gorczmski, R.M., Macrae, S., Kennedy, M. 1982. Conditioned Immune Response Associated with Allogeneic Skin Grafts in Mice. J. Immunol. 129: 704–709.

    Google Scholar 

  15. Gorczinski, R.M., Kennedy, M., and Ciampi, A., 1985, Cimetidine reverses tumor growth enhancement of plasmacytoma tumors in mice demonstrating conditioned immunosuppression. J. Immunol. 134 (6): 4261–4266.

    Google Scholar 

  16. Guillemin, R., Cohn, M., and Melnechuk, T., Eds., 1985, Neural Modulation of Immunity, Raven Press, N.Y.

    Google Scholar 

  17. Hadden, J.W., 1983, Advances in Immunopharmacology II, Hadden, J.W., Chedid, L., Dukov, P., Sperifico, S., Willoughby, D., Eds., Pergamon Press, Oxford.

    Google Scholar 

  18. Idova, G. V. and Cheido, M.A., 1985, Redistribution of suppressor cells in the basis of immunomodulating action of the monoamine systems in Neuroimmunomodulation (Pro ceedings of the First International Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  19. Janković, B.D., Jakulić, S., and Horvat, J. 1982, Delayed skill hypersensitivity reactions to human S-100 protein in psychiatric patients. Biol. Psychiatry, 17:687 ff.

    PubMed  Google Scholar 

  20. Janković, B.D. and Spector, N.H., 1985, Lesions and stimulation of the nervous system: effects upon the immune system in Enkephalins and endorphins in Stress and the Immune System. N.K. Plotnikoff, Ed., Plenum, N.Y.

    Google Scholar 

  21. Jenkins, P.E., Chadwick, R.A., and Nevin, J.A. 1983, Classical conditioned enhancement of antibody production. Bull. Psyconomic Soc. 21 (6): 485–487.

    Google Scholar 

  22. Kerza-Kwiatecki, A.P. 1985, Conference Report: First International Workshop on Neuroimmunomodulation (NIM) in Trends in Neuroscience.

    Google Scholar 

  23. Kerza-Kwiatecki, A.P. and Paterson, P., in press, 1985, Meeting Report: First International Neuroimmunomodulation (NIM) Workshop, in Clin. Immun. and Immunopathology.

    Google Scholar 

  24. Korneva, E.A., Klimenko, V.M., and Shkinek, E.K., 1985, Neurohumoral Maintenance of Immune Homeostasis. Translated and Edited by S.A. Corson and E. O’L. Corson. University of Chicago Press.

    Google Scholar 

  25. Krueger, J.M., 1985, Interleukin-1: A promotor of slow-wave sleep. Neuroimmunomodulation: (Proceedings of the First InternaTIonal Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  26. Levy, S.M., Ed., 1982, Biological Mediators of Behavior and Disease: Neoplasia Elsevier, N.Y.

    Google Scholar 

  27. Locke, S. Ader, R., Besedovsky, H., Hall, N., Solomon, G., Strom, T., Spector, N.H., Eds. 1985, Foundations of Psychoneuroimmunology, Aldine, N.Y.

    Google Scholar 

  28. Locke, S., and Hornig-Rohan, 1983, Mind and Immunity. Institute for the Advancement of Health, N.Y.

    Google Scholar 

  29. Luk’yanenko, V.I., 1961, The problem of conditioned-reflex regulation of immunologic reactions. Ups. Sovrem. Biol. 51(2):170–187 (Russian).

    Google Scholar 

  30. Metal’nikov, S., 1934, Role du Systeme Neryeux et de de Facteurs Biologiques et Psychiques dans l’Immunite. Masson, Paris.

    Google Scholar 

  31. Metal’nikov, S., and Chorine, V., 1926, The role of conditioned reflexes in immunity. Ann Inst. Pasteur 40:893–900, (original in French: English translation in Locke et al, cited above).

    Google Scholar 

  32. Oppenheim, J.J. and Gery, I., 1982. Interleukin I is more than an Interleukin. Immunology Today 3: 113–119.

    Article  CAS  Google Scholar 

  33. Peeke, H.V.S., Dark, K., Ellman, G., McCurry, C, Russell, M., and Salfi, M., 1985, Blood Histamine Levels and Conditioning of an Allergic Response in Guinea Pigs, in Neuroimmunomodulation: (Proceedings of the First International Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  34. Pierpaoli, W., 1985, Immunoregulatory and morphostatic function of bone-marrow derived factors. In Neural Modulation of Immunity, R. Guillemin et al, Eds., Raven Press, N.Y.

    Google Scholar 

  35. Pierpaoli, W., and Maestroni, G.J.M., 1978, Pharmacological control of the hormonally modulated immune response. Immunology 34:419, 430.

    PubMed  CAS  Google Scholar 

  36. Plonikoff, N. et al, Eds., in press, 1985, Enkephalins and Endorphins: Stress and the Immne System, Plenum, N.Y.

    Google Scholar 

  37. Renoux, G., Biziere, K., and Renoux, M., 1985, Imuthiol Reveals Brain Cortical Asymmetry in the Regulation of T-Cell Activities, in Neuroimmunomodulation: (Proceedings of the First International Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  38. Russell, M., Dark, K.A., Cummins, R.W., Ellman, G., Callaway, E., and Peeke, H.V.S., 1984, Learned histamine release. Science 222: 733–734.

    Article  Google Scholar 

  39. Smith, E.M., and Blalock, J.E., 1985, Lymphocyte Production of Neurally Active Pituitary Hormone-Like Molecules in Neuroimmunomodulation: (Proceedings of the First International Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  40. Solomon, G., 1985, Psychoneuroimmunology, in Encyclopedia of Neuroscience, G. Adelman, Ed., Birhauser, Boston.

    Google Scholar 

  41. Solvason, H.B., Ghanta, V., Hiramoto, R., and Spector, N.H., 1985, Natural Killer Cell Activity Augmented by Classical Pavlovian Conditioning in Neuroimmunomodulation: (Proceedings of the First International Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  42. Spector, N.H., 1979, The NIM Newsletter 1:1, Bethesda.

    Google Scholar 

  43. Spector, N.H., 1980, The central state of the hypothalamus in health and disease; old and new directions, in Physiology of the Hypothalamus, P. Morgane and J. Panksepp, Eds., Dekker, N.Y.

    Google Scholar 

  44. Spector, N.H. and E. Korneva, 1981, Neurophysiology, immunophysiology and neuroimmunomodulation, in Psycho neuroimmunology, R. Ader, Ed., Academic Press, N.Y.

    Google Scholar 

  45. Spector, N.H. 1983, Anatomic and physiologic connections between the central nervous and immune systems: Neuroimmunomodulation in Immunoregulation, Plenum, N.Y.

    Google Scholar 

  46. Spector, N.H., 1984~ Summary and concluding remarks, in International Conference on Regulation of Immune Homeostasis, E.A. Korneva, Ed. (Russian), Leningrad.

    Google Scholar 

  47. Spector, N.H., 1984, Neuroimmunomodulation of reactions to viral or pseudo-viral antigens, in Stress, Immunity and Aging, E.L. Cooper, Ed., Marcel Dekker, N.Y.

    Google Scholar 

  48. Spector, N.H., 1985, Neuroimmunomodulation, Encyclopedia of Neuroscience, G. Adelman, Ed., Birkhauser, Boston.

    Google Scholar 

  49. Spector, N.H., 1985, Information explosions in an old-new research domain, in The Year in Immunology, 1984–1985, Cruse, J.M. and Lewis, R.E., Jr., Eds., Karger, Basel.

    Google Scholar 

  50. Spector, N.H., Fox, B.H., Monjan, A.A., Bulloch, K., Pierpaoli, W., and Janković, B.D., in press 1985, Neuroimmunomodulation: (Proceedings of the First International Workshop on NIM), IWGN, Bethesda.

    Google Scholar 

  51. Spector, N.H., Fox, B.H., Monjan, A.A., Bulloch, K. Pierpaoli, W. and Janković, B.D., in press 1985, Neuroimmunomodulation, Gordon and Breach, Glasgow.

    Google Scholar 

  52. Tobler, I., Borbely, A.A., Schwyzer, M., and Fontana, A. Interleukin-1 derived from astrocytes enhances slow-wave activity in sleep EEG of the rat. Eur. J. Immunol. 104 (1–2): 191–192, 1984.

    CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Fundamental Neurosciences Program, NINCDS, National Institutes of Health, Bethesda, Maryland, 22205, USA

    Novera Herbert Spector Ph.D.

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  1. Novera Herbert Spector Ph.D.
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Editor information

Editors and Affiliations

  1. Monsanto Company, St. Louis, Missouri, USA

    Robert C. A. Frederickson Ph.D. (Senior Director) (Senior Director)

  2. Central Nervous System Research Searle Research and Development, G. D. Searle & Co., Skokie, Illinois, USA

    Robert C. A. Frederickson Ph.D. (Senior Director) (Senior Director)

  3. Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA, 46223

    Hugh C. Hendrie M. B. Ch.B. (Chairman and Albert E. Sterne Professor of Psychiatry) (Chairman and Albert E. Sterne Professor of Psychiatry)

  4. Section of Applied and Theoretical Neurobiology The Institute of Psychiatric Research and Departments of Psychiatry and Biochemistry, Indiana University School of Medicine Indiana University Medical Center, Indianapolis, Indiana, USA, 46223

    Joseph N. Hingtgen Ph.D. (Professor of Psychology and Neurobiology) (Professor of Psychology and Neurobiology)

  5. Departments of Pharmacology & Toxicology & Psgchiatry Program in Medical Neurobiologg, Indiana University School of Medicine, Indianapolis, Indiana, USA, 46223

    Morris H. Aprison Ph.D. (Distinguished Professor of Neurobiology and Biochemistry) (Distinguished Professor of Neurobiology and Biochemistry)

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© 1986 Matinus Nijhoff Publishing, Boston

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Spector, N.H. (1986). Interactions Among the Nervous, Endocrine and Immune Systems (Nim). In: Frederickson, R.C.A., Hendrie, H.C., Hingtgen, J.N., Aprison, M.H. (eds) Neuroregulation of Autonomic, Endocrine and Immune Systems. Topics in the Neurosciences, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2315-0_16

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  • DOI: https://doi.org/10.1007/978-1-4613-2315-0_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9424-5

  • Online ISBN: 978-1-4613-2315-0

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