Abstract
The word ‘cure’was used in the title of Hal stead’s paper in 1894 in which he described his technique of radical mastectomy (1) and this had so powerful an effect that the treatment remained standard for the next 50 years. There appeared to be little practical point in investigating factors which might be related to prognosis since patients received identical treatment whether their outlook was good or bad. Clinical or pathological staging was used mainly to compare results between centres but was not used to determine treatment. Histological grading was used as an academic excercise.
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© 1986 Martinus Nijhoff Publishing, Boston
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Bulbrook, R.D. et al. (1986). Tumour and patient variables as Indicators of Prognosis. The silent period. In: Rich, M.A., Hager, J.C., Taylor-Papadimitriou, J. (eds) Breast Cancer: Origins, Detection, and Treatment. Developments in Oncology, vol 43. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2309-9_22
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DOI: https://doi.org/10.1007/978-1-4613-2309-9_22
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