Fluctuation Analysis Applied to Nonstationary Biological Processes
According to the standard theory of the statistics of stationary’ shot noise’ (ie. a fluctuating signal produced by the linear summation of elementary events occurring randomly at a constant mean rate), the mean value, variance and skew of the noise are related to the mean rate of the events, <r>, their amplitude, h, and their time course, w(t), by the following equations: mean=<r>h∫w(t)dt, variance=<r>h2∫w2(t)dt, skew=<r>h3∫w3(t)dt (Rice, 1944).
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