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Calcium Independent Quantal Transmitter Release at the Neuromuscular Junction

  • S. Thesleff
  • M. T. Lupa
Part of the Topics in the Neurosciences book series (TNSC, volume 1)

Abstract

It is generally accepted that transmitter release at the neuromuscular junction is a calcium-requiring process, calcium ions being necessary for depolarization-transmitter secretion coupling to occur (29). Nerve impulse-evoked multi-quantal release of acetylcholine (ACh), giving rise to the end-plate potential (e.p.p.), as well as the spontaneous quantal secretion of ACh, causing the miniature end-plate potentials (m.e.p.ps), depend on extra- and intracellular calcium concentrations (see 20; 28; 40).

Keywords

Botulinum Toxin Neuromuscular Junction Extensor Digitorum Longus Transmitter Release Intracellular Calcium Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1986

Authors and Affiliations

  • S. Thesleff
    • 1
  • M. T. Lupa
    • 1
  1. 1.Department of PharmacologyUniversity of LundLundSweden

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