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Resting Calcium Levels and Evoked Release at the Neuromuscular Junction

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Calcium, Neuronal Function and Transmitter Release

Part of the book series: Topics in the Neurosciences ((TNSC,volume 1))

Abstract

In 1967 Dodge and Rahamimoff (1) proposed a model for the relation between [Ca2+] out and transmitter release at the neuromuscular junction that has dominated subsequent work on this problem. We have modified their model by adding one additional parameter: the level of Ca in the resting nerve terminal. This single addition substantially alters the behavior of the model and makes it necessary to reinterpret many previous measurements. We have presented the mathematics for the model elsewhere (2, 3). Here we will give a more general description of our model, its application to experiments, and some directions for future research.

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Authors
  1. W. Van Der Kloot
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  2. I. S. Cohen
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  3. S. B. Barton
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Editor information

Editors and Affiliations

  1. The Hebrew University, Jerusalem, Israel

    Rami Rahamimoff

  2. University College London, London, England

    Bernard Katz

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© 1986 Martinus Nijhoff Publishing, Boston

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Van Der Kloot, W., Cohen, I.S., Barton, S.B. (1986). Resting Calcium Levels and Evoked Release at the Neuromuscular Junction. In: Rahamimoff, R., Katz, B. (eds) Calcium, Neuronal Function and Transmitter Release. Topics in the Neurosciences, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2307-5_11

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  • DOI: https://doi.org/10.1007/978-1-4613-2307-5_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9420-7

  • Online ISBN: 978-1-4613-2307-5

  • eBook Packages: Springer Book Archive

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