Metastatic Colorectal Carcinoma: Pathobiologic Subsets

  • Lewis A. Johnson
Part of the Developments in Oncology book series (DION, volume 42)


The principal pathologic variables of colorectal cancer prognosis are reviewed. The interrelationship of the three variables, namely, tumor stage, tumor grade, and tumor cell type, is emphasized. Survival prognosis is very much influenced by the histologic/cytologic characteristics of the tumor with greater importance being placed on tumor grade and the predominant cell type present in metastatic colon cancer. The criteria, definition, and examples of the histologic grade and cell types are presented. The potential implications of these pathologic characteristics to therapeutic modalities are hypothesized.


Colorectal Adenocarcinoma Survival Prognosis Tumor Cell Type Metastatic Colon Cancer Predominant Cell Type 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Martinus Nijhoff Publishing, Boston 1986

Authors and Affiliations

  • Lewis A. Johnson

There are no affiliations available

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