Endoscopic Laser Surgery for Colonic Neoplasia

  • John H. Bowers
  • Randall W. Burt
  • John A. Dixon
Part of the Developments in Oncology book series (DION, volume 42)

Summary

The potential role of endoscopically directed light amplification by stimulated emission of radiation (LASER) surgery for the palliative treatment of colorectal neoplasms and adenomas in selected patients is reviewed. This technique relies on the precise thermal destruction of exposed tissue. The depth of penetration is determined by the wavelength of the incident laser source, most commonly the argon laser or the neodymium YAG laser. In selected patients, because of the size configuration or location of a lesion, laser surgery appears to be a safe alternative to endoscopic diathermic removal or incisional surgery. This procedure has been well tolerated without complications. Nevertheless, the encouraging preliminary experience reported here is best regarded as palliative treatment.

Keywords

Argon Adenocarcinoma Adenoma Luminal Perforation 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Kelly DF, Bown SO, Salmon PR, Calder BM, Pearson H, Weaver BMQ: The nature and extent of biological changes induced by argon laser photocoagulation in canine gastric mucosa. Gut 22: 1047–1055, 1980.CrossRefGoogle Scholar
  2. 2.
    Bown SG, Salmon PR, Storey DW, Calder BM, Kelly DF, Adams N, Pearson H, Weaver BMQ: Nd:YAG laser photocoagulation in the dog stomach. Gut 21: 818–825, 1980.PubMedCrossRefGoogle Scholar
  3. 3.
    Piercey JRA, Auth DC, Silverstein FE, Willard HR, Dennis MB, Ellefson DM, Davis DM, Protell RL, Rubin CE: Electrosurgical treatment of experimental bleeding canine gastric ulcers: Development and testing of a computer control and a better electrode. Gastroenterology 527–534, 1978.Google Scholar
  4. 4.
    Dixon JA, Burt RW, Rotering RH, McCloskey DW: Endoscopic argon laser photocoagulation of sessile colonic polyps. Gastrointest Endose 28: 162–165, 1982.CrossRefGoogle Scholar
  5. 5.
    Protell RL, Silverstein FE, Auth DL, Dennis MB, Gilbert DA, Rubin CE: The Nd: YAG is dangerous for photocoagulation of experimental bleeding gastric ulcers when compared with the argon laser (Abstract). Gastroenterology 1080, 1978.Google Scholar
  6. 6.
    Dixon JA, Berenson MM, McCloskey DW: Neodymium-YAG laser treatment of experimental canine gastric bleeding. Acute and chronic studies of photocoagulation, penetration and perforation. Gastroenterology 77: 647–731, 1979.PubMedGoogle Scholar
  7. 7.
    Lambert R, Sabben G: Laser therapy in colorectal tumors: Early results ( Abstract ). Gastroenterology 1223, 1983.Google Scholar
  8. 8.
    Brunetaud JM, Mosquet L, Bourez J, Triboulet JP, Delmotte JS, Cortot A: Laser applications in nonhemorrhagic digestive lesions. In K Atsumi (ed). New Frontiers in Laser Medicine and Surgery. Excerpta Medica, Amsterdam, 1983, pp 455–461.Google Scholar
  9. 9.
    Kiefhaber P, Kiefhaber K: Present endoscopic laser therapy in the gastrointestinal tract. In K Atsumi (ed). New Frontiers in Laser Medicine and Surgery. Excerpta Medica, Amsterdam, 1983, pp 439–H6.Google Scholar
  10. 10.
    Erbe RW: Inherited gastrointestinal polyposis syndromes. N Engl J Med 294: 1101–1106, 1976.PubMedCrossRefGoogle Scholar
  11. 11.
    Spinelli P, Pizzetti P, Mirabile V, Marchesini R, Andreola S, Fava G, Emanuelli H: Neodymium-YAG laser treatment of the rectal remnant after colectomy for familial polyposis. In: K Atsumi and N Nimsakul (eds), Laser-Tokyo ’81, Japan Society for Laser Medicine, Tokyo, 1981, pp 23–49, 23–30.Google Scholar
  12. 12.
    Wolff WI, Shinya H: Endoscopic polypectomy. Cancer 36: 683–690, 1975.CrossRefGoogle Scholar
  13. 13.
    Schrock TR: Management of the discovered colon lesion. Gastrointest Endose 26 (Suppl): 365–375, 1980.CrossRefGoogle Scholar
  14. 14.
    Fleischer DE, Kessler F, Haye O: Endoscopic laser therapy for carcinoma of the esophagus: A new palliative approach. Am J Surg 143: 280–283, 1982.PubMedCrossRefGoogle Scholar
  15. 15.
    Bown SG, Swain CP, Edwards DAW, Salmon PR: Palliative relief of malignant upper gastrointestinal obstruction by endoscopic laser therapy (Abstract). Gut 23: A918, 1982.Google Scholar
  16. 16.
    Harada K, Mizushima K, Namiki M, Kasai S, Mito M: Endoscopic YAG laser treatment of lesions in the distal colon with experimental studies (Abstract). In: K Atsumi and N Nimsakul (eds), Laser-Tokyo ’81, Tokyo. Japan Society for Laser Medicine, 1981, pp 20–32.Google Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1986

Authors and Affiliations

  • John H. Bowers
  • Randall W. Burt
  • John A. Dixon

There are no affiliations available

Personalised recommendations