Abstract
Considering the metastasis as a highly complexed process both on the level of heterogeneity of tumor cell population and host environmental factors involved, it is very difficult to select a satisfactory experimental model and an approach to be applied to the given research program. In our motivation to study an immnnobiological aspects of metastasis which could be relevant to improved, more rational designing of combined experimental therapy, we have considered several points, to mention just two: 1. to have the tumor variants which differ utmostly in their metastatic properties, but remain similar in their other traits, 2. to possess the tumor cells variants accessible for biochemical and serological analysis of their surface characteristics.
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© 1986 Martinus Nijhoff Publishing, Boston
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Radzikowski, C., Duś, D., Opolski, A., Strządała, L. (1986). Characteristics of LL2 and its Lectin-Resistant not Metastasizing Variants. In: Lapis, K., Liotta, L.A., Rabson, A.S. (eds) Biochemistry and Molecular Genetics of Cancer Metastasis. Developments in Oncology, vol 41. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2299-3_19
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DOI: https://doi.org/10.1007/978-1-4613-2299-3_19
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