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Diagnostic Procedures in the Detection of CNS Metastases from Small Cell Lung Cancer

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Lung Cancer: Basic and Clinical Aspects

Part of the book series: Cancer Treatment and Research ((CTAR,volume 28))

Abstract

Central nervous system (CNS) metastases occur frequently as a complication of small cell carcinoma of the lung (SCLC). Their importance relates primarily to the considerable adverse impact which they exert on the well-being of afflicted patients. Of secondary importance is the possibility that tumor tissue may survive within the confines of the CNS despite eradication of tumor elsewhere in the body, thereby limiting the prospects for long-term survival and cure. This secondary issue was first raised by Hansen in 1973 [1] when it was suggested that an increase in median survival would lead to an increase in the frequency of CNS metastases, as had been the case following improvements in the treatment of acute lymphatic luekemia in children.

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Pedersen, A.G. (1986). Diagnostic Procedures in the Detection of CNS Metastases from Small Cell Lung Cancer. In: Hansen, H.H. (eds) Lung Cancer: Basic and Clinical Aspects. Cancer Treatment and Research, vol 28. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2295-5_9

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