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High-Dose Chemotherapy for Small Cell Lung Cancer

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Lung Cancer: Basic and Clinical Aspects

Part of the book series: Cancer Treatment and Research ((CTAR,volume 28))

Abstract

Initially, the introduction of chemotherapy in the treatment of small cell lung cancer (SCLC) has considerably improved the bad prognosis of the patients with this highly malignant tumor [1]. The change of a median survival of less than 3 months before chemotherapy into more than one year as a result of its introduction, and the observation of the occurrence of two year disease free survival, be it only in a small number of patients, led half a decade ago to speculations that the goal of cure in a larger number of these patients might be within reach [2]. Since that time however, no further progress has been made and the therapeutic results are still on the same plateau as five years ago. This disappointing reality necessitates the investigation of other therapeutic approaches and in this chapter the results of high-dose chemotherapy (HDCT) will be summarised and discussed.

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© 1986 Martinus Nijhoff Publishers, Boston

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Postmus, P.E., Sleijfer, D.T., Mulder, N.H. (1986). High-Dose Chemotherapy for Small Cell Lung Cancer. In: Hansen, H.H. (eds) Lung Cancer: Basic and Clinical Aspects. Cancer Treatment and Research, vol 28. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2295-5_13

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  • DOI: https://doi.org/10.1007/978-1-4613-2295-5_13

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