Abstract
The acceptance of IVF-ET as a treatment modality for certain types of infertility in the human has triggered a flurry of activity in providing a patient service, in applied research endeavors designed primarily to improve clinical pregnancy rates and in basic research in reproductive endocrinology and physiology. This paper outlines the state of the art in technologic and research frontiers associated with these endeavors.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abate, V., Call, A., and Stanchi, A. 1984. Endometrial biopsy at the time of embryo transfers: Correlation of histologic diagnosis with therapy and pregnancy rates. Fertil. Steril. 41: 43S.
Botero-Ruiz, W., Laufer, N., DeCherney, A.H., Polan, M.L., Haseltine, F.P., and Behrman, H.R. 1984. The relationship between follicular fluid steroid concentration and successful fertilization of human oocytes in vitro. Fertil. Steril. 41: 820–826.
Byrd, W., and Wolf, D.P. 1984. Evaluation of capacitation in human sperm using monoclonal antibodies against acrosomal cap antigens. Biol. Reprod. 30: 90.
Edwards, R.G., Bavister, B.D., and Steptoe, P.C. 1969. Early stages of fertilization in vitro of human oocytes matured in vitro. Nature 221: 632.
Edwards, R.G., Steptoe, P.C., and Purdy, J.M. 1980. Establishing full-term human pregnancies using cleaving embryos grown in vitro. Brit. J. Obstet. Gynaecol. 87: 737.
Fishel, S.B., Edward, R.G., and Walters, D.E. 1983. Follicular steriods as a prognosticator of successful fertilization of human oocytes in vitro. J. Endocr. 99: 335–344.
Isahakia, M. and Alexander, N.J. 1984. Interspecies cross-reactivity of monoclonal antibodies directed against human sperm antigens. Biol. Reprod. 30: 1015–1026.
Jones, G.S. 1984. Update on in vitro fertilization. Endocrine Reviews 5: 62–75.
Kerin, J.F.P., Peek, J., Warties, G.M., Kirby, C., Jeffrey, R., Matthews, C.D., and Cox, L.W. 1982. Improved conception rate after intrauterine insemination of washed spermatozoa from men with poor quality semen. Lancet 1: 533–534.
Lee, C-Y.G., Huang, Y-S., Huang, C-H., Hu, P-C., and Menge, A.C. 1982. Monoclonal antibodies to human sperm antigens. J. Reprod. Immunol. 4: 173–181.
Lopata, A., Johnston, I.W.H., Hoult, I.J., Speirs, A.I. 1980. Pregnancy following interuterine implantation of an embryo obtained by in vitro fertilization of a preovulatory egg. Fertil. Steril. 33: 117.
Lutjen, P., Trounson, A., Leeton, J., Findlay, J., Wood, C., and Renou, P. 1984. The establishment and maintenance of pregnancy using in vitro fertilization and embryo donation in a patient with primary ovarian failure. Nature 307: 174–175.
Mortimer, D., Courtot, A.M., Giovangrandi, Y., Jeulin, C., and David, G. 1984. Human sperm motility after migration into, and incubation in, synthetic media. Gamete Research 9: 131–144.
Quigley, M.M., Maklad, N.F., and Wolf, D.P. 1983. Comparison of two clomiphene citrate dosage regimens for follicular recruitment in an in vitro fertilization program. Fertil. Steril. 40: 178–182.
Rufo, G.A., Jr., Singh, J.P., Babcock, D.F., and Lardy, H.A. 1983. Purification and characterization of a calcium transport inhibitor protein from bovine seminal plasma. J. Biol. Chem. 257–4627.
Steptoe, P.C., and Edwards, R.G. 1970. Laparoscopic recovery of preovulatory human oocytes after priming of ovaries with gonadotropins. Lancet 1: 683.
Steptoe, P.C., and Edwards, R.G. 1976. Reimplantation of a human embryo with subsequent tubal pregnancy. Lancet 1: 880.
Trounson, A., and Mohr, L. 1983. Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo. Nature 305: 707–709.
Trounson, A.O., Mohr, L.R., Wood, C., and Leeton, J.F. 1982. Effect of delayed insemination on in vitro fertilization, culture and transfer of human embryos. J. Reprod. Fert. 64: 285.
Veeck, L.L., Wortham, J.W.E., Witmyer, J., Sandow, B.A., Acosta, A.A., Garcia, J.E., Jones, G.S., Jones, H.W., Jr. 1983. Maturation and fertilization of morphologically immature human oocytes in a program of in vitro fertilization. Fertil. Steril. 39: 594–602.
Wolf, D.P., Byrd, W., Dandekar, P., and Quigley, M.M. 1984. Sperm concentration and the fertilization of human eggs in vitro. Biol. Reprod. Biol. Reprod. 31: 837.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Plenum Press, New York
About this chapter
Cite this chapter
Wolf, D.P. (1986). Research Frontiers in Human In Vitro Fertilization. In: Hedrick, J.L. (eds) The Molecular and Cellular Biology of Fertilization. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2255-9_23
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2255-9_23
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9320-0
Online ISBN: 978-1-4613-2255-9
eBook Packages: Springer Book Archive