Abstract
The toxicity of lipopolysaccharide (LPS) isolated from different organisms varies greatly, as does the toxicity of different salt forms of a single LPS isolate (4). Thus, it seems probable that the “endotoxic effects” of LPS are due to the presence of particular chemical groups, and to the accessibility of these groups. The accessibility may, in turn, depend on the aggregate structure.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
R. T. Coughlin, C. R. Caldwell, A. Haug, and E. J. McGroarty, A cationic electron spin resonance probe used to analyze cation interactions with lipopolysaccharide, Biochem. Biophys. Res. Comm. 100: 1137 (1981).
R. C. Goldman and L. Leive, Heterogeneity of antigenic-side-chain length in lipopolysaccharide for Escherichia coli 0111 and Salmonella typhimurium LT2, Eur. J. Biochem. 107: 145 (1980).
L. Leive, The barrier function of gram negative envelope, Ann. NY Acad. Sci. 235: 109 (1974).
O. Luderitz, M. A. Freudenberg, C. Galanos, V. Lehmann, E.Th. Rietschel, and D. H. Shaw, Lipopolysaccharides of gram-negative bacteria, Curr. Top. Membr. Transp. 17: 79 (1982).
R. S. Munford, C. L. Hall, and P. D. Rick, Size heterogeneity of Salmonella typhimurium lipopolysaccharide in outer membranes and culture supernatant membrane fragments, J. Bacteriol. 144: 630 (1980).
H. Nikaido, Outer membranes of Salmonella typhimurium, transmembrane diffusion of some hydrophobic substances, Biochim. Biophys. Acta. 433: 118 (1976).
H. Nikaido and M. Vaara, Molecular basis of bacterial outer membrane permeability, Microbiol. Rev. 49: 1 (1985).
E. T. Pava and P. H. Makela, Lipopolysaccharide heterogeneity in Salmonella typhimurium analyzed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis, Eur. J. Biochem. 107: 137 (1980).
A. A. Peterson, R. E. W. Hancock, and E. J. McGroarty, Binding of cationic antibiotics to lipopolysaccharides of Pseudomonas aeruginosa, in preparation (1985).
A. A. Peterson, R. E. W. Hancock, and E. J. McGroarty, Binding of cationic antibiotics to lipopolysaccharides of Pseudomonas aeruginosa, in preparation (1985).
A. A. Peterson and E. J. McGroarty, Decreased binding of antibiotics to lipopolysaccharides from polymyxin-resistant strains of Escherichia coli and Salmonella typhimurium, in preparation (1985).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Plenum Press, New York
About this chapter
Cite this chapter
Peterson, A.A., McGroarty, E.J. (1986). Physical Properties of Short-Chain and Long-Chain Fractions of Lipopolysaccharide. In: Szentivanyi, A., Friedman, H., Nowotny, A. (eds) Immunobiology and Immunopharmacology of Bacterial Endotoxins. University of South Florida International Biomedical Symposia Series, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2253-5_7
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2253-5_7
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9319-4
Online ISBN: 978-1-4613-2253-5
eBook Packages: Springer Book Archive