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The Release of Immunopotentiating Mediators from Macrophages Activated by Endotoxins

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Immunobiology and Immunopharmacology of Bacterial Endotoxins

Part of the book series: University of South Florida International Biomedical Symposia Series ((EMISS,volume 18))

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Abstract

The infection of mice with murine leukemia viruses often results in an acquired immunodeficiency state in which active immune responses are impaired. The Friend leukemia virus (FLV), which consists of a lymphatic leukemia virus complexed with a spleen focus-forming virus, is a murine oncornavirus which suppresses both humoral and cell mediated responses (2,10,11). In the past it was generally accepted that the suppression of the ability to develop specific antibody responses was due to the interaction of the virus with antibody producing plasma cells or their precursors.

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References

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Authors and Affiliations

  1. Departments of Medical Microbiology and Immunology at Arlington Hospital, Arlington, Virginia, USA

    R. Christopher Butler, Jeri M. Frier & Mrunal S. Chapekar

  2. Departments of Medical Microbiology and Immunology at University of South Florida College of Medicine, Tampa, Florida, USA

    Herman Friedman

  3. Departments of Medical Microbiology and Immunology at University of Pennsylvania Medical Center for Oral Health Research, Philadelphia, Pennsylvania, USA

    Alois Nowotny

Authors
  1. R. Christopher Butler
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  2. Jeri M. Frier
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  3. Mrunal S. Chapekar
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  4. Herman Friedman
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  5. Alois Nowotny
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Editor information

Editors and Affiliations

  1. University of South Florida College of Medicine, Tampa, Florida, USA

    Andor Szentivanyi (Dean of the College of Medicine Deputy Vice President for Medical Affairs Professor of Pharmacology and Internal Medicine Chairman of the Department of Pharmacology and Therapeutics) & Herman Friedman (Professor and Chairman) (Dean of the College of Medicine Deputy Vice President for Medical Affairs Professor of Pharmacology and Internal Medicine Chairman of the Department of Pharmacology and Therapeutics) &  (Professor and Chairman)

  2. University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Alois Nowotny

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© 1986 Plenum Press, New York

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Butler, R.C., Frier, J.M., Chapekar, M.S., Friedman, H., Nowotny, A. (1986). The Release of Immunopotentiating Mediators from Macrophages Activated by Endotoxins. In: Szentivanyi, A., Friedman, H., Nowotny, A. (eds) Immunobiology and Immunopharmacology of Bacterial Endotoxins. University of South Florida International Biomedical Symposia Series, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2253-5_33

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  • DOI: https://doi.org/10.1007/978-1-4613-2253-5_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9319-4

  • Online ISBN: 978-1-4613-2253-5

  • eBook Packages: Springer Book Archive

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