Abstract
It is obvious for an investigator in the field of resistance to bacterial infections that specific antibody formation has its limitations as a defense mechanism. A primary immune response is the end product of a sequence of events and would occur too late to rescue the host in many septicemias, which is even more evident if we consider neonatal resistance. Antibody formation is probably one of the highest forms of protein synthesis in evolution (13,17). In contrast, other major defense mechanisms such as phagocytosis or elevation of temperature have been shown to be more powerful and more anciently established in many phylogenetic studies (17).
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© 1986 Plenum Press, New York
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Chedid, L., Parant, M., Parant, F., Riveau, G. (1986). Nonspecific Effects of LPS on Bacterial Infections. In: Szentivanyi, A., Friedman, H., Nowotny, A. (eds) Immunobiology and Immunopharmacology of Bacterial Endotoxins. University of South Florida International Biomedical Symposia Series, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2253-5_16
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DOI: https://doi.org/10.1007/978-1-4613-2253-5_16
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