Abstract
The increasingly complex repertoire of differentiated cell types found in higher organisms, and the capacity for flexible response to different developmental and physiological requirements, both lean upon the provision of families of molecules with similar but not identical properties. This is achieved by the evolution of gene families following a continuous process of duplication and divergence, so that a study of the evolution of proteins Is essential for understanding the evolution of differentiation. We are forced to consider two different problems in thinking about this phenomenon: one is the evolutionary relationships of the structural proteins and the way in which the range of molecular properties which have become available are related to the developmental characteristics which have evolved. The second problem concerns the evolutionary changes in the regulation of these related genes since, by definition, we could not expect that they should all be transcribed simultaneously and in equal amounts. (Dayhoff, 1 972; Niall, 1982; Li, 1983; Jeffreys et al., 1983).
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© 1986 Plenum Press, New York
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Clayton, R.M., Truman, D.E.S. (1986). Introduction. In: Clayton, R.M., Truman, D.E.S. (eds) Coordinated Regulation of Gene Expression. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2245-0_25
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DOI: https://doi.org/10.1007/978-1-4613-2245-0_25
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