The Life Span of Patients with Primary (AL) Amyloidosis and the Effect of Colchicine Treatment
There is no specific treatment for any variety of amyloidosis . Primary (AL) amyloidosis, now the more commonly seen form of the disorder, usually has a poor prognosis and short life expectancy . Colchicine, which effectively prevents acute fibril attacks in patients with familial Mediterranean fever (FMF), a condition that predisposes to amyloidosis, has been shown to block amyloid production in the mouse model [3,4]. In addition, reports indicate that patients with FMF receiving colchicine no longer develop amyloidosis and suggest improvement in some amyloidotic patients with this form of AA amyloid [5, 6].
KeywordsPlacebo Arthritis Creatinine Pneumonia Peri
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