Abstract
One of the most difficult problems in the clinical judgement of cancer patients is the determination of the effectiveness of any treatment modality. This is particularly apparent in the evaluation of solid malignancies of the gastrointestinal tract. In 1966, Drs. Lemon and Foley proposed the slow infusion of one gram of 5FU for periods of eight hours daily for 14 days followed by weekly bolus I-V injections of .5 grams 5FU in l0cc of dilutent. They felt that this method was not only effective but also avoided the frequent severe iatrogenic complications of current anti-neoplastic chemotherapy.
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Reference
Engelfinger, F.J., 1966, Controversies in Internal Medicine, W. B. Saunders, Philadelphia, London, Toronto
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© 1986 Plenum Press, New York
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Steinberg, D. (1986). Long Term Appraisal of the Lemon-Foley Method of Chemotherapy of Solid Tumors of the Gastrointestinal Tract. In: Rosenthal, C.J., Rotman, M. (eds) Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2197-2_14
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DOI: https://doi.org/10.1007/978-1-4613-2197-2_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9291-3
Online ISBN: 978-1-4613-2197-2
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