Skip to main content

Behavioral Teratogenesis Resulting from Early Cadmium Exposure

  • Chapter
Handbook of Behavioral Teratology

Abstract

Cadmium is a pollutant of considerable concern, not only in the industrial setting, but also in the environment. In addition to the acute and chronic toxicities associated with its use in industrial and manufacturing processes, cadmium (Cd), because of its exceptional ability to accumulate in living organisms, also represents an increasing hazard for the population in general.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Altman, J., Sudarshan, K., Das, G. D., McCormick, N., & Barnes, D. The influence of nutrition on neural and behavioral development: III. Development of some motor, particularly locomotor, patterns during infancy. Developmental Psychobiology, 1971, 4, 91–114.

    Google Scholar 

  • Baranski, B. Behavioral alterations in offspring of female rats repeatedly exposed to cadmium oxide by inhalation. Toxicology Letters, 1984, 22, 53–61.

    Article  PubMed  Google Scholar 

  • Baranski, B., Stetkiewicz, I., Sitarek, K., & Szymczak, W. Effects of oral, subchronic cadmium administration on fertility, prenatal and postnatal progeny development in rats. Archives of Toxicology, 1983, 54, 297–302.

    Article  PubMed  Google Scholar 

  • Bell, J. U., & Waalkes, M. P. Role of hepatic metallothionein during perinatal development in the rat. In E. Foulkes (Ed.), Biological roles of metallothionein. New York: Elsevier/North Holland Biomedical Press, 1982.

    Google Scholar 

  • Bremner, I. Heavy metal toxicities. Quarterly Reviews of Biophysics, 1974, 55, 75–124.

    Article  Google Scholar 

  • Bremner, I. Mammalian absorption, transport and excretion of cadmium. In M. Webb (Ed.), The chemistry, biochemistry and biology of cadmium. New York: Elsevier/North-Holland Biochemical Press, 1979.

    Google Scholar 

  • Cooper, G. P., Choudhury, H., Hastings, L., & Petering, H. G. Prenatal cadmium exposure: Effects on essential trace metals and behavior in rats. In D. D. Mahlum, M. R. Sikov, P. L. Hackett, & F. D. Andrew (Eds.), Developmental toxicology of energy-related pollutants. National Technical Information Service, U.S. Department of Energy, 1978.

    Google Scholar 

  • Cory-Slechta, D. A., & Weiss, B. Adversiveness of cadmium. Neurotoxicology, 1981, 2, 711–724.

    PubMed  Google Scholar 

  • Coyle, I., Wayner, M. J., & Singer, G. Behavioral teratogenesis: A critical evaluation. Pharmacology, Biochemistry, and Behavior, 1976, 4, 191–200.

    Article  PubMed  Google Scholar 

  • Dobbing, J., & Sands, J. Vulnerability of the developing brain: IX. The effect of nutritional growth retardation on the timing of the brain growth spurt. Biology of the Neonate, 1971, 19, 363–378.

    Article  PubMed  Google Scholar 

  • Elinder, C. G., Kjellstrom, T., & Friberg, L. Cadmium in kidney cortex, liver, and pancreas from Swedish autopsies. Archives of Environmental Health, 1976, 31, 292–302.

    PubMed  Google Scholar 

  • Ferm, V. H., & Carpenter, S. J. The relationship of cadmium and zinc in experimental mammalian teratogenesis. Laboratory Investigation, 1968, 18, 429–432.

    PubMed  Google Scholar 

  • Friberg, L. Proteinuria and kidney injury among workman exposed to cadmium and nickel dust. Journal of Industrial Hygiene and Toxicology, 1948, 30, 32–36.

    PubMed  Google Scholar 

  • Friberg, L. Health hazards in the manufacture of alkaline accumulators with special reference to chronic cadmium poisoning. Acta Medica Scandinavica, 1950, 138, Suppl. 240.

    Google Scholar 

  • Friberg, L., Piscator, M., Nordberg, G. F., & Kjellstrom, T. Cadmium in the environment ( 2nd ed. ). Cleveland: CRC Press, 1974.

    Google Scholar 

  • Gabbiani, G., Baic, D., & Deziel, C. Toxicity of cadmium for the central nervous system. Experimental Neurology, 1967, 18, 154–160.

    Article  PubMed  Google Scholar 

  • Gabbiani, G., Gregory, A., & Baic, D. Cadmium-induced selective lesion of sensory ganglia. Journal of Neuropathology and Experimental Neurology, 1967, 26, 498–506.

    Article  PubMed  Google Scholar 

  • Glover, J., & Jacobs, A. Activity pattern of iron deficient rats. British Medical Journal, 1972, 2, 627–628.

    Article  PubMed  Google Scholar 

  • Gunn, S. A., & Gould, T. C. Cadmium and other mineral elements. In A. D. Johnson, W. R. Gnomes, & N. L. Van Demark (Eds.), The testes. New York: Academic Press, 1970.

    Google Scholar 

  • Hastings, L., Choudhury, H., Petering, H. G., & Cooper, G. P. Behavioral and biochemical effects of low-level prenatal cadmium exposure in rats. Bulletin of Environmental Contamination and Toxicology, 1978, 20, 96–101.

    Article  PubMed  Google Scholar 

  • Kostial, K., Kargacin, B., & Landeka, M. Influence of dietary ingredients on the body retention of strontium, cadmium, and mercury in suckling rats. Toxicology Letters, 1984, 23, 163–168.

    Article  PubMed  Google Scholar 

  • Kullander, S., & Kallen, B. A prospective study of smoking and pregnancy. Acta Obstetrica et Gynecologica Scandinavica, 1971, 50, 83–94.

    Article  Google Scholar 

  • Lee, I. P., & Dixon, R. L. Effects of cadmium on spermatogenesis studied by velocity sedimnentation cell separation and serial mating. Journal of Pharmacology and Experimental Therapeutics, 1973, 187, 641–657.

    PubMed  Google Scholar 

  • Lucis, O. J., Lucis, R., & Shaikh, Z. A. Cadmium and zinc in pregnancy and lactation. Archives of Environmental Health, 1972, 25, 14–22.

    PubMed  Google Scholar 

  • Mennear, J. H. Cadmium toxicity. New York: Marcel Dekker, 1979.

    Google Scholar 

  • Murthy, L., Rice, D. P., & Petering, H. G. Sex differences with respect to the accumulation of oral cadmium in rats. In R. Kirchgessner (Ed.), Trace element metabolism in man and animals, Vol. 3. Freishing- Weihenstephen, West Germany: Technical University of Munich Press, 1978.

    Google Scholar 

  • Newland, M. C., Ng, W. W., Miller, R. K., Baggs, R. B., & Weiss, B. Selective effects of neonatal exposure to cadmium chloride on adult operant behavior in rats. Neurobehavioral Toxicology and Teratology, 1984, 6, 179.

    Google Scholar 

  • Parizek, J. The destructive effect of cadmium ion on testicular tissue and its prevention by zinc. Journal of Endocrinology, 1957, 15, 56–63.

    Article  PubMed  Google Scholar 

  • Perry, H. M., & Erlanger, M. W. Metal-induced hypertension following chronic feeding of low doses of cadmium and mercury. Journal of Laboratory and Clinical Medicine, 1974, 83, 541–547.

    PubMed  Google Scholar 

  • Prigge, E. Early signs of oral and inhalative uptake of cadmium in rats. Archives of Toxicology, 1978, 40, 231–247.

    Article  PubMed  Google Scholar 

  • Rafales, L. Locomotor activity in neurotoxicological assessment. In Z. Annau (Ed.), Behavioral toxicology. Baltimore: Johns Hopkins Press, 1986.

    Google Scholar 

  • Rastogi, R. B., Merali, Z., & Singhal, R. L. Cadmium alters behavior and the biosynthetic capacity for catacholamines and serotonin in neonatal rat brain. Journal of Neurochemistry, 1977, 28, 789–794.

    Article  PubMed  Google Scholar 

  • Schroeder, H. A., & Mitchener, M. Toxic effects of trace elements on the reproduction of mice and rats. Archives of Environmental Health, 1971, 23, 102–106.

    PubMed  Google Scholar 

  • Schroeder, H. A., & Vinton, W. H. Hypertension induced in rats by small doses of cadmium. American Journal of Physiology, 1962, 202, 515–517.

    PubMed  Google Scholar 

  • Shaikh, Z. A. Metallothionein as a storage protein for cadmium: Its toxicological implications. In E. Foulkes (Ed.), Biological roles of metallothionein. New York: Elsevier/North Holland Biomedical Press, 1982.

    Google Scholar 

  • Shaikh, Z. A., & Smith, L. M. Biological indicators of cadmium exposure and toxicity. Experientia, 1984, 40, 36–43.

    Article  PubMed  Google Scholar 

  • Smith, M. J., Pihl, R. O., & Garber, B. Postnatal cadmium exposure and long-term behavioral changes in the rat. Neurobehavioral Toxicology and Teratology, 1982, 4, 283–287.

    PubMed  Google Scholar 

  • Smith, M. J., Garber, B., & Pihl, R. O. Altered behavioral response to apomorphine in cadmium exposed rats. Neurobehavioral Toxicology and Teratology, 1983, 5, 161–165.

    PubMed  Google Scholar 

  • Sonawane, B. R., Norberg, M., Norberg, G. F., & Lucier, G. W. Placental transfer of cadmium in rats: Influence of dose and gestational age. Environmental Health Perspectives, 1975, 12, 97–102.

    Article  PubMed  Google Scholar 

  • Stonard, M. D., & Webb, M. Influence of dietary cadmium on the distribution of the essential metals, copper, zinc, and iron in tissues of the rat. Chemico-Biological Interactions, 1976, 15, 349–363.

    Article  PubMed  Google Scholar 

  • Webb, M. The chemistry, biochemistry, and biology of cadmium. New York: Elsevier/North Holland Biomedical Press, 1979.

    Google Scholar 

  • Webster, W. S. Cadmium-induced fetal growth retardation in the mouse. Archives of Environmental Health, 1978, 33, 36–42.

    PubMed  Google Scholar 

  • Weigel, H. J., Elmadfa, I., & Jager, H. J. The effect of low doses of dietary cadmium oxide on the disposition of trace elements (zinc, copper, iron), hematological parameters, and liver functions in rats. Archives of Environmental Contamination and Toxicology, 1984, 13, 289–296.

    Article  PubMed  Google Scholar 

  • Wong, K., & Klaassen, C. D. Neurotoxic effects of cadmium in young rats. Toxicology and Applied Pharmacology, 1982, 63, 330–337.

    Article  PubMed  Google Scholar 

  • Wong, K., Cachia, R., & Klaassen, C. D. Comparison of the toxicity and tissue distribution of cadmium in newborn and adult rats after repeated administration. Toxicology and Applied Pharmacology, 1980, 56, 317–325.

    Article  PubMed  Google Scholar 

  • Zenick, H., Hastings, L., Goldsmith, M., & Niewenhuis, R. J. Chronic cadmium exposure: Relation to male reproductive toxicity and subsequent fetal outcome. Journal of Toxicology and Environmental Health, 1982, 9, 377–387.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Plenum Press, New York

About this chapter

Cite this chapter

Hastings, L. (1986). Behavioral Teratogenesis Resulting from Early Cadmium Exposure. In: Riley, E.P., Vorhees, C.V. (eds) Handbook of Behavioral Teratology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2189-7_14

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2189-7_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9288-3

  • Online ISBN: 978-1-4613-2189-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics