AF64A Induced Cholinotoxicity: Behavioral and Biochemical Correlates
The postulated involvement of the cholinergic system in Alzheimer’s disease (AD) has highlighted the research and therapeutic approach of this affliction during the last decade (1). There is little doubt at the present stage that a clear hypofunction of the cholinergic system is in evidence in certain brain areas in AD patients. Other neurotransmitter systems seem to be relatively unaffected (1).
KeywordsMorris Water Maze Passive Avoidance Dark Compartment Passive Avoidance Test ChAT Activity
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