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AF64A Induced Cholinotoxicity: Behavioral and Biochemical Correlates

  • R. Brandeis
  • Z. Pittel
  • C. Lachman
  • E. Heldman
  • S. Luz
  • S. Dachir
  • A. Levy
  • I. Hanin
  • A. Fisher
Part of the Advances in Behavioral Biology book series (ABBI, volume 29)

Abstract

The postulated involvement of the cholinergic system in Alzheimer’s disease (AD) has highlighted the research and therapeutic approach of this affliction during the last decade (1). There is little doubt at the present stage that a clear hypofunction of the cholinergic system is in evidence in certain brain areas in AD patients. Other neurotransmitter systems seem to be relatively unaffected (1).

Keywords

Morris Water Maze Passive Avoidance Dark Compartment Passive Avoidance Test ChAT Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • R. Brandeis
    • 1
  • Z. Pittel
    • 1
  • C. Lachman
    • 1
  • E. Heldman
    • 1
  • S. Luz
    • 1
  • S. Dachir
    • 1
  • A. Levy
    • 1
  • I. Hanin
    • 2
  • A. Fisher
    • 1
  1. 1.Israel Institute for Biological ResearchNess-ZionaIsrael
  2. 2.Loyola University Stritch School of MedicineChicagoUSA

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