Neuroimaging Studies of Alzheimer’s Disease
To a large extent in vivo structural brain studies of Alzheimer’s disease (AD) have been restricted to estimates of dilation of the cerebral ventricles and the cortical sulci. While there are consistently reported increases in these areas in normal aging and in AD patients, when compared with age matched normal controls there is considerable overlap. As a result, these estimates are of limited diagnostic value (de Leon and George, 1983).
KeywordsWhite Matter Computerize Tomography Number Cortical Sulcus Regional Cerebral Oxygen Normal Aged Control
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