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Clinical Heterogeneity in Patients with Dementia of the Alzheimer Type

  • Richard Mayeux
  • Yaakov Stern
Part of the Advances in Behavioral Biology book series (ABBI, volume 29)

Abstract

Clinical criteria for the diagnosis of dementia of the Alzheimer type (DAT) vary considerably in the current literature (1–4). Most investigators develop uniform criteria in order to be certain of homogeneity within a given cohort of patients for research purposes. Restricted criteria can lead to refinement in diagnosis, particularly when supported by careful postmortem verification (4–6). In view of this, several investigations are currently in progress to develop both qualitative and quantitative clinical and diagnostic measures for use in DAT.

Keywords

Alzheimer Type Extrapyramidal Sign Restricted Criterion Motor Manifestation Hachinski Ischemic Score 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Richard Mayeux
    • 1
  • Yaakov Stern
    • 1
  1. 1.College of Physicians and Surgeons Neurological InstituteColumbia UniversityNew YorkUSA

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