Abstract
The use of porphyrin preparations in conjunction with visible light in Photodynamic Therapy (PDT) is dependent on two important properties exhibited by these compounds, i.e. their preferential uptake and localisation in malignant tissue and the fact that such porphyrins are very efficient photosensitisers. By direct absorption of light they are electronically excited to higher energy levels from which they can, by energy transfer processes, donate this energy to acceptor molecules giving porphyrin deactivation and elevation of acceptor to excited states possibly not attainable by direct absorption under these conditions.
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© 1985 Plenum Press, New York
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Redmond, R.W., Land, E.J., Truscott, T.G. (1985). Aggregation Effects on the Photophysical Properties of Porphyrins in Relation to Mechanisms Involved in Photodynamic Therapy. In: Kessel, D. (eds) Methods in Porphyrin Photosensitization. Advances in Experimental Medicine and Biology, vol 193. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2165-1_28
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DOI: https://doi.org/10.1007/978-1-4613-2165-1_28
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