Molecular and Cellular Aspects of the Interaction of Benzimidazole Carbamate Pesticides with Microtubules

  • Edward H. Byard
  • Keith Gull


For about twenty years, benzimidazole drugs have enjoyed wide commercial applications as systemic fungicides, as broad spectrum anthelmintics against cestode and nematode infections, and as antitumoral agents. The range of benzimidazole derivatives that became available was limited only by the resources of the drug firms, and the skill of the organic chemists. The effectiveness of these drugs is well established: they have performed well in field and clinical trials, and are commercially successful. However, it is only recently, and certainly within the last ten years that the mechanism of their action has been studied in any systematic way. Basic science is now catching up to commercial pragmatism!!


Parasitic Nematode Aspergillus Nidulans Slime Mold Microtubule Assembly Benzimidazole Derivative 
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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Edward H. Byard
    • 1
  • Keith Gull
    • 1
  1. 1.Biological LaboratoryUniversity of KentCanterbury, KentEngland

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