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Hormone-Producing Tumors of the Ovary and Placenta

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Gynecologic Endocrinology

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Abstract

As the ovary and placenta are endocrine organs, any neoplastic lesion arising from them may be active in hormone production. Although rare, they present interesting and challenging problems to clinicians. Hormone-producing ovarian tumors make up approximately 5% of all ovarian tumors. The histological diversity of these tumors is great and includes both primary and metastatic tumors of the ovary. Table 25–1 classifies these hormone-producing tumors into five major categories. Although androgens and estrogens are the most common hormones secreted by these tumors, human chorionic gonadotropin (hCG), thyroxine (T4), serotonin, and human placental lactogen (hPL) may be secreted as well. The clinical presentation is therefore extremely interesting in many of these cases. Although in vivo and in vitro studies of hormone production as well as ultrastructural studies have increased our understanding of these tumors, the histogenesis and pathophysiology of many of these tumors remains poorly understood.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Ohio State University Hospitals, Columbus, Ohio, 43210, USA

    Frank E. Chang & Moon H. Kim

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  1. Frank E. Chang
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  2. Moon H. Kim
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Editors and Affiliations

  1. University of Illinois College of Medicine, Chicago, Illinois, USA

    Jay J. Gold M.D., F.A.C.P (Clinical Professor of Medicine and Adjunct Professor of Obstetrics and Gynecology) (Clinical Professor of Medicine and Adjunct Professor of Obstetrics and Gynecology)

  2. Department of Obstetrics and Gynecology, UMDNJ-New Jersey Medical School, Newark, New Jersey, USA

    John B. Josimovich M.D. (Professor and Vice-Chairman) (Professor and Vice-Chairman)

  3. Department of Pathology, UMDNJ-New Jersey Medical School, Newark, New Jersey, USA

    John B. Josimovich M.D. (Professor and Vice-Chairman) (Professor and Vice-Chairman)

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© 1987 Plenum Publishing Corporation

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Chang, F.E., Kim, M.H. (1987). Hormone-Producing Tumors of the Ovary and Placenta. In: Gold, J.J., Josimovich, J.B. (eds) Gynecologic Endocrinology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2157-6_25

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  • DOI: https://doi.org/10.1007/978-1-4613-2157-6_25

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9272-2

  • Online ISBN: 978-1-4613-2157-6

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