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Cervical Mucus

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Gynecologic Endocrinology

Abstract

Cervical mucus is a gel-like material that fills the endocervical canal and controls the entry of spermatozoa and microorganisms into the upper genital tract. The functions of the cervical mucus are dependent on its physical properties and the presence of key enzymes and other proteins.

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References

  1. Weiss G: Effect of steroid hormones on cervical mucus, in Briggs MH (ed): Advances in Steroid Biochemistry and Pharmacology, Vol I. London, Academic, 1970, pp 137–162.

    Google Scholar 

  2. Schumacher GFB: Humoral immune factors in the female reproductive tract and their changes during the cycle, in Dhindsa DS, Schumacher GFB (eds): Immunological Aspects of Infertility and Fertility Regulation. New York, Elsevier/North-Holland, 1980, pp 93–141.

    Google Scholar 

  3. Hafez ESE: The cervix and sperm transport, in Hafez ESE (ed): Human Reproduction. Conception and Contraception, 2nd ed. Hagerstown, MD, Harper & Row, 1980, pp 221–252.

    Google Scholar 

  4. Fordney-Settlage D: A review of cervical mucus and sperm interactions in humans. Int J Fertil 26: 161–169, 1981.

    PubMed  CAS  Google Scholar 

  5. Joyce D, Vassilopoulos D: Sperm-mucus interaction and artificial insemination. Clin Obstet Gynaecol 8: 587–610, 1981.

    PubMed  CAS  Google Scholar 

  6. Chantier E: Structure and function of cervical mucus, in Chantier EN, Elder JB, Elstein M (eds): Mucus in Health and Disease—II. New York, Plenum, 1982, pp 251–263.

    Google Scholar 

  7. Elstein M: Cervical mucus: Its physiological role and clinical significance, in Chantier EN, Elder JB, Elstein M (eds): Mucus in Health and Disease—II. New York, Plenum, 1982, pp 301–318.

    Google Scholar 

  8. Kroeks MVAM, Kremer J: The pH of the lower third of the genital tract, in Insler V, Bettendorf G (eds): The Uterine Cervix in Reproduction. Stuttgart, Thieme, 1977, pp 109–118.

    Google Scholar 

  9. Odeblad E: The functional structure of human cervical mucus. Acta Obstet Gynecol Scand 47 (suppl l): 59–79, 1968.

    Google Scholar 

  10. Davis KP, Maciulla GJ, Yannane ME, et al: Cervical mucus immunoglobulins as an indicator of ovulation. Fertil Steril 62: 388–392, 1983.

    CAS  Google Scholar 

  11. Moghissi KS: Prediction and detection of ovulation. Fertil Steril 34: 89–98, 1980.

    PubMed  CAS  Google Scholar 

  12. Tsibris JCM, Thomason JL, Kunigk A, et al: Guaiacol peroxidase levels in human cervical mucus: A possible predictor of ovulation. Contraception 25: 59–67, 1982.

    Article  PubMed  CAS  Google Scholar 

  13. Charbonnel B, Kremer M, Gerozissis K, et al: Human cervical mucus contains large amounts of prostaglandins. Fertil Steril 38: 109–111, 1982.

    PubMed  CAS  Google Scholar 

  14. Moreno-Escallon B, Chappel S, Blasco L: Luteinizing hormone in cervical mucus. Fertil Steril 37: 536–541, 1982.

    PubMed  CAS  Google Scholar 

  15. Wolf DP, Sokoloski JE, Litt M: Composition and function of human cervical mucus. Biochim Biophys Acta 630: 545–558, 1980.

    PubMed  CAS  Google Scholar 

  16. Yurewicz EC, Matsuura F, Moghissi KS: Structural characterization of neutral oligosaccharides of human midcycle mucins. J Biol Chem 257: 2314–2322, 1982.

    PubMed  CAS  Google Scholar 

  17. Carlstedt I, Lingren H, Sheehan JK, et al: Isolation and characterization of human cervical mucus glycoproteins. Biochem J 211: 13–22, 1983.

    PubMed  CAS  Google Scholar 

  18. Allen A: Mucus—A protective secretion of complexity. Trends Biochem Sci 9: 169–173, 1983.

    Article  Google Scholar 

  19. Creeth JM: Constituents of mucus and their separation. Br Med Bull 34: 17–24, 1978.

    PubMed  CAS  Google Scholar 

  20. Daunter B, Lutjen P: Cervical mucus, in Hafez ESE, Ken- emans P (eds): Atlas of Human Reproduction by Scanning Electron Microscopy. Lancaster, England, MTP Press, 1982, pp 55–59.

    Google Scholar 

  21. Gibbons RA, Seilwood R: The macromolecular biochemis¬try of cervical secretions, in Blandau RJ, Moghissi K (eds): The Biology of the Cervix. Chicago, The University of Chicago Press, 1973, pp 251–265.

    Google Scholar 

  22. Hanson FW, Overstreet JW: The interaction of human spermatozoa with cervical mucus in vivo. Am J Obstet Gynecol 140: 173–178, 1981.

    PubMed  CAS  Google Scholar 

  23. Gould JE, Overstreet JW, Hanson FW: Assessment of human sperm function after aging in vitro. Fertil Steril 35:240, 1981. (abst)

    Google Scholar 

  24. Sparks RA, Puppier BGA, Watt PJ, et al: Bacteriological colonization of uterine cavity: Role of tailed intrauterine contraceptive device. Br Med J 282: 1189–1191, 1981.

    Article  CAS  Google Scholar 

  25. Zuckerman H, Kahana A, Carmel S: Antibacterial activity of human cervical mucus. Gynecol Invest 6: 265–271, 1975.

    Article  PubMed  CAS  Google Scholar 

  26. Jones WR: Immunology of infertility. Clin Obstet Gynecol 8: 611–638, 1981.

    CAS  Google Scholar 

  27. Katz DF, Overstreet JW, Houson FW: A new quantitative test for sperm penetration in cervical mucus. Fertil Steril 33: 179–186, 1980.

    PubMed  CAS  Google Scholar 

  28. McSweeney DJ, Sbarra AJ: A new cervical mucus test for hormone appraisal. Am J Obstet Gynecol 88: 705–709, 1964.

    PubMed  CAS  Google Scholar 

  29. Tsibris JCM, Trujillo YP, Fernandez BB, et al: Distribution of guaiacol peroxidase in human endometrium and endocer- vical epithelium during the menstrual cycle. J Clin Endocrinol Metab 54: 991–997, 1982.

    Article  PubMed  CAS  Google Scholar 

  30. Tsibris JCM, Langenberg PC, Khan-Dawood FS, et al: Cer- vicovaginal peroxidases: Sex hormone control and potential clinical uses. Fertil Steril 44: 236–240, 1985.

    PubMed  CAS  Google Scholar 

  31. Tsibris JCM, Virgin SD, Khan-Dawood FS, et al: Cer- vicovaginal peroxidases: Markers of the fertile period. Obstet Gynecol 67: 316–320, 1986.

    PubMed  CAS  Google Scholar 

  32. Bayse GS, Michaels AW, Morrison M: The peroxidase- catalyzed oxidation of tyrosine. Biochim Biophys Acta 284: 34–42, 1972.

    PubMed  CAS  Google Scholar 

  33. Aeschbach R, Amado R, Neukom H: Formation of di- tyrosine cross-links in proteins by oxidation of tyrosine residues. Biochim Biophys Acta 439: 292–301, 1976.

    PubMed  CAS  Google Scholar 

  34. Foerder CA, Shapiro BM: Release of ovoperoxidase from sea urchin eggs hardens the fertilization membrane with tyrosine cross-links. Proc Natl Acad Sci USA 74:4214– 4218, 1977.

    Google Scholar 

  35. Check JH, Adelson HG, Wu CH: Improvement of cervical mucus with guaifenesin. Fertil Steril 37: 707–708, 1982.

    PubMed  CAS  Google Scholar 

  36. Merriam GR, Lipsett MB (eds): Catechol Estrogens. New York, Raven, 1983.

    Google Scholar 

  37. Tsibris JC, Fort FL, Cantor B, et al: The uneven distribution of estrogen and progesterone receptors in human endometrium. J Steroid Biochem 14: 997–1003, 1981.

    Article  PubMed  CAS  Google Scholar 

  38. Tsibris JCM, Thomason JL, Gold JJ, et al: Le mucus cervical et sa teneur en guaiacol péroxidase: un procédé possible pour prédire l’ovulation. Contraception Fertil Sexual 11: 25–27, 1983.

    CAS  Google Scholar 

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© 1987 Plenum Publishing Corporation

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Tsibris, J.C.M. (1987). Cervical Mucus. In: Gold, J.J., Josimovich, J.B. (eds) Gynecologic Endocrinology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2157-6_10

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  • DOI: https://doi.org/10.1007/978-1-4613-2157-6_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9272-2

  • Online ISBN: 978-1-4613-2157-6

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