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The Cellular Basis of Amphibian Gastrulation

  • Chapter
Book cover The Cellular Basis of Morphogenesis

Part of the book series: Developmental Biology ((DEBO,volume 2))

Abstract

Amphibian gastrulation is a complex integration of local cellular behavior to produce a supracellular system that, in turn, constrains and organizes the behavior of individual cells. Such behavior has fascinated and challenged embryologists for over a hundred years and has also perplexed some of them to the point of thinking it not reducible to part-processes. These thoughts were expressed by Walter Vogt (translated in Spemann, 1938), who did more than anyone to characterize the early morphogenesis of amphibians:

It does not appear at all as if cells were walking in the sense, that single part movements were combining to form the movements of the masses; for even the most natural and plausible explanation by means of amoeboid moving of single cells fails utterly. We evidently have not the wandering of cells before us, but rather a passive obedience to a superior force.

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  1. Department of Zoology, University of California-Berkely, 94720, Berkely, California, USA

    Ray E. Keller

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  1. University of Calgary, Calgary, Alberta, Canada

    Leon W. Browder

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Keller, R.E. (1986). The Cellular Basis of Amphibian Gastrulation. In: Browder, L.W. (eds) The Cellular Basis of Morphogenesis. Developmental Biology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2141-5_7

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