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Synthesis and Separation of cis- and trans-3-Ethylproline; Polymerization and Conformational Studies of Poly trans-3-Ethyl-D-Proline

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Advances in Polymer Synthesis

Part of the book series: Polymer Science and Technology ((POLS,volume 31))

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Abstract

The study of the conformational behavior of polypeptides has intrinsic interest in a complex and challenging theoretical and experimental problem. There are also strong biological implications inasmuch as there are many known naturally occurring polypeptides, both linear and cyclic, with potent effects as hormones, toxins, antibiotics, and ionophores. It is very probable that these functions are closely related to the polymer chain conformations.1–5 Investigations of model polypepetides have been extremely useful for the interpretation of conformational behavior and for the elucidation of the interaction between proteins and other macromolecules. The conformational structures of polyproline and related compounds have been of particular interest due to the important role L-proline plays in effecting protein structure.

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Author information

Authors and Affiliations

  1. Department of Chemistry and the Macromolecular Research Center, The University of Michigan, Ann Arbor, MI, 48109, USA

    Omar Tiba & C. G. Overberger

Authors
  1. Omar Tiba
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  2. C. G. Overberger
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Editor information

Editors and Affiliations

  1. Ashland Chemical Company, Columbus, Ohio, USA

    Bill M. Culbertson

  2. Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA

    James E. McGrath

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© 1985 Plenum Press, New York

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Tiba, O., Overberger, C.G. (1985). Synthesis and Separation of cis- and trans-3-Ethylproline; Polymerization and Conformational Studies of Poly trans-3-Ethyl-D-Proline. In: Culbertson, B.M., McGrath, J.E. (eds) Advances in Polymer Synthesis. Polymer Science and Technology, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2121-7_21

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  • DOI: https://doi.org/10.1007/978-1-4613-2121-7_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9254-8

  • Online ISBN: 978-1-4613-2121-7

  • eBook Packages: Springer Book Archive

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