Passive Avoidance Training in the Chick
The young chick is a particularly appropriate model for the study of the cell biology of learning and memory. Work from our laboratory during the last 5 years has shown that, following a simple one-trial learning task in the day-old chick, region- specific synaptic events, measurable biochemically and morphologically, occur. These events are summarized herein, and evidence is discussed suggesting that they are not merely nonspecific concomitants of learning but are part of the biological language in which memory is coded in the central nervous system.
KeywordsChrome Serotonin Leucine Acetylcholine Colchicine
Unable to display preview. Download preview PDF.
- Aleksidze, N., Potempska, A., Murphy, S., and Rose, S. P. R., 1981, Passive avoidance in the young chick affects forebrain a-bungarotoxin and serotonin binding, Abstr. 8th ISN, p. 382382.Google Scholar
- Benowitz, L., 1980, Functional organization of the avian telencephalon, in: Comparative Neurology of the Telencephalon (S. Ebbeson, ed.), Plenum Press, New York.Google Scholar
- Bradley, P. and Horn, G. 1979, Efferent connections of hyperstriatum ventrale in the chick, J. Anat. 128:414–415.Google Scholar
- Coulter, J. C., 1982, Thesis: Open University, Milton Keynes.Google Scholar
- McCabe, N. and Rose, S. P. R., 1985, Passive avoidance training increases fucose incorporation into glycoprotein in chick forebrain slices in vitro, Neurochem Res. (in press).Google Scholar
- Rose, S. P. R., 1982, From causations to translations: A dialectical solution to a reductionist enigma, in: Towards a Liberatory Biology (S. P. R. Rose, ed.), Allison & Busby, London, pp. 10–25.Google Scholar
- Rose, S. P. R., 1984, Strategies in studying the cell biology of learning and memory, in: The Neuropsy¬chology of Memory (L. R. Squire and N. Butters, eds.), Guilford Press, New York, pp. 547–559.Google Scholar
- Rose, S. P. R. and Csillag, A., 1985, Passive avoidance training results in lasting changes in deoxy- glucose metabolism in left hemisphere regions of chick brain, Behav. Neural Biol, (in press).Google Scholar
- Rose, S. P. R. and Haywood, J., 1976, Experience, learning and brain metabolism in: Biochemical Correlates of Brain Structure and Function (A.N. Davison, ed.), Academic Press, London, pp. 249–292.Google Scholar
- Sokoloff, L., Reivich, M., Kennedy, C., Des Rosiers, M. H., Patlak, C. S., Pettigrew, K. D., Sakurada, O., and Shinohara, M., 1977, the 14C-deoxyglucose method for the measurement of local cerebral glucose utilisation: Theory, procedure and normal values in the conscious and anaethetized albino rat, J. Neurochem 28:897–916.CrossRefGoogle Scholar
- Stewart, M. G., Rose, S. P. R., and King, T. S., 1984a, A stereological investigation of synapses in chick palaeostriatum augmentatum and lobus parolfactorius following training on a passive avoidance task, Acta Stereologica 21(Suppl. I):227–230.Google Scholar
- Tillson, P. and Rose, S. P. R., 1981, Passive avoidance training results in region specific changes in incorporation of 14C-leucine into chick forebrain total protein but not into actin, Abstr. 8th I.S.N., p. 399.Google Scholar